PAM16 and ARL6IP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PAM16	ARL6IP1
Description		presequence translocase associated motor 16	ADP ribosylation factor like GTPase 6 interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	PAM Complex, Tim23 Associated Import Motor TIM23 Mitochondrial Import Inner Membrane Translocase Complex Mitochondrial Matrix Extrinsic Component Of Mitochondrial Inner Membrane Protein-containing Complex	Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Ossification Protein Import Into Mitochondrial Matrix Negative Regulation Of ATPase Activity Negative Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Apoptotic DNA Fragmentation	Positive Regulation Of L-glutamate Import Across Plasma Membrane Cotranslational Protein Targeting To Membrane Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Endoplasmic Reticulum Tubular Network Formation Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Membrane Organization
Pathways		Mitochondrial protein import
Drugs
Diseases
GWAS		Erectile dysfunction ( 30583798)
Interacting Genes		9 interacting genes: ARL6IP1 BLOC1S2 CEP70 DNAJC19 DNMT3B FEZ1 GPM6A MRFAP1 PGRMC1	41 interacting genes: ACSF2 ARL4D ARL6 CERT1 DIABLO FBXW7 FDFT1 FXR2 GAD2 GOLPH3 GOLPH3L GORASP2 HGS HMGCL INPP5K LMNA MTERF3 MYG1 NAPB NDRG4 NUDT3 PAM16 PBX3 RAB33A RETREG3 SENP2 SHMT2 SNX1 SNX10 SNX11 SNX12 SNX15 SNX3 SNX4 SPG21 SUCLA2 TFAM TUFM WIPI2 ZFYVE21 ZNF391
Entrez ID		51025	23204
HPRD ID		14798	09641
Ensembl ID		ENSG00000217930	ENSG00000170540
Uniprot IDs		Q9Y3D7	A0A024QYV7 Q15041
PDB IDs
Enriched GO Terms of Interacting Partners?
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