ARL6IP1 and SNX10

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ARL6IP1	SNX10
Description		ADP ribosylation factor like GTPase 6 interacting protein 1	sorting nexin 10
Image		No pdb structure
GO Annotations	Cellular Component	Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane	Nucleus Endoplasmic Reticulum Centrosome Secretory Granule Extrinsic Component Of Endosome Membrane Apical Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding 1-phosphatidylinositol Binding ATPase Binding
	Biological Process	Positive Regulation Of L-glutamate Import Across Plasma Membrane Cotranslational Protein Targeting To Membrane Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Endoplasmic Reticulum Tubular Network Formation Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Membrane Organization	Gastric Acid Secretion Endocytosis Endosome Organization Protein Transport Bone Mineralization Osteoclast Differentiation Tooth Eruption Bone Resorption Calcium Ion Homeostasis Cilium Assembly Protein Localization To Cilium Protein Localization To Centrosome Ruffle Assembly Cellular Response To Leukemia Inhibitory Factor
Pathways
Drugs
Diseases
GWAS			Dental caries (decayed, missing and filled teeth) ( 31533690) HDL cholesterol ( 30275531) Metabolic syndrome ( 31589552) Metabolite levels ( 23823483) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		41 interacting genes: ACSF2 ARL4D ARL6 CERT1 DIABLO FBXW7 FDFT1 FXR2 GAD2 GOLPH3 GOLPH3L GORASP2 HGS HMGCL INPP5K LMNA MTERF3 MYG1 NAPB NDRG4 NUDT3 PAM16 PBX3 RAB33A RETREG3 SENP2 SHMT2 SNX1 SNX10 SNX11 SNX12 SNX15 SNX3 SNX4 SPG21 SUCLA2 TFAM TUFM WIPI2 ZFYVE21 ZNF391	2 interacting genes: ARL6IP1 RABAC1
Entrez ID		23204	29887
HPRD ID		09641	15409
Ensembl ID		ENSG00000170540	ENSG00000086300
Uniprot IDs		A0A024QYV7 Q15041	A0A024RA70 B4DJM0 Q8N5Z3 Q9Y5X0
PDB IDs			4ON3 4PZG
Enriched GO Terms of Interacting Partners?
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