ARL6IP1 and NDRG4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ARL6IP1	NDRG4
Description		ADP ribosylation factor like GTPase 6 interacting protein 1	NDRG family member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane	Cytoplasm Mitochondrion Endoplasmic Reticulum Membrane Cytosol Basolateral Plasma Membrane Cell Projection Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Molecular_function Protein Binding
	Biological Process	Positive Regulation Of L-glutamate Import Across Plasma Membrane Cotranslational Protein Targeting To Membrane Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Endoplasmic Reticulum Tubular Network Formation Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Membrane Organization	Heart Looping Signal Transduction Brain Development Visual Learning Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Negative Regulation Of Smooth Muscle Cell Migration Cell Differentiation Embryonic Heart Tube Development Vesicle Docking Negative Regulation Of Smooth Muscle Cell Proliferation Cardiac Muscle Cell Proliferation Cell Migration Involved In Heart Development Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Endocytic Recycling
Pathways
Drugs
Diseases
GWAS			Electrocardiographic traits ( 20062063) QT interval ( 22726844 19305408 19305409) Schizophrenia ( 29483656)
Interacting Genes		41 interacting genes: ACSF2 ARL4D ARL6 CERT1 DIABLO FBXW7 FDFT1 FXR2 GAD2 GOLPH3 GOLPH3L GORASP2 HGS HMGCL INPP5K LMNA MTERF3 MYG1 NAPB NDRG4 NUDT3 PAM16 PBX3 RAB33A RETREG3 SENP2 SHMT2 SNX1 SNX10 SNX11 SNX12 SNX15 SNX3 SNX4 SPG21 SUCLA2 TFAM TUFM WIPI2 ZFYVE21 ZNF391	6 interacting genes: AGTRAP ARL6IP1 CMTM5 MAL2 REEP6 RTN3
Entrez ID		23204	65009
HPRD ID		09641	14817
Ensembl ID		ENSG00000170540	ENSG00000103034
Uniprot IDs		A0A024QYV7 Q15041	A0A024R6V8 A0A0S2Z5L7 A0A0S2Z5R7 B7Z9X4 Q9ULP0
PDB IDs
Enriched GO Terms of Interacting Partners?
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