PBX3 and MAL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PBX3	MAL2
Description		PBX homeobox 3	mal, T cell differentiation protein 2 (gene/pseudogene)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Transcription Factor Complex	Endomembrane System Integral Component Of Membrane Apical Plasma Membrane Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific	Protein Binding Structural Constituent Of Myelin Sheath
	Biological Process	Regulation Of Respiratory Gaseous Exchange By Neurological System Process Anterior Compartment Pattern Formation Posterior Compartment Specification Respiratory Gaseous Exchange Adult Locomotory Behavior Dorsal Spinal Cord Development Positive Regulation Of Transcription By RNA Polymerase II Neuron Development	Myelination Transcytosis
Pathways
Drugs
Diseases
GWAS		Dentures ( 31235808) Medication use (opioids) ( 31015401) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Pulse pressure ( 30578418) Response to mTOR inhibitor (everolimus) ( 24009623) Sleep duration ( 30531941) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 30224653 30578418)	Blood pressure (smoking interaction) ( 25189868) Gallstone disease ( 30504769) Hippocampal atrophy ( 19668339) Osteoprotegerin levels ( 25080503)
Interacting Genes		15 interacting genes: AGTRAP ARL6IP1 CNTRL FSD2 HOXA9 HOXB8 MAGEA1 MAGEC2 MAL2 MEIS1 RABAC1 TPM3 TRAF1 TRIM44 ZNHIT3	21 interacting genes: ABCG8 ARFIP2 CREB3 FAM3A GAD1 GAD2 NDRG4 PBX3 PIMREG PPP1CA PTPN9 RAB37 S100B SH3GL1 SHMT2 TBRG4 TPD52 TPD52L1 TPD52L2 TUBB VARS2
Entrez ID		5090	114569
HPRD ID		15938	14351
Ensembl ID		ENSG00000167081	ENSG00000147676
Uniprot IDs		P40426 Q5JS98 Q96AL5	A0A024R9E4 Q969L2
PDB IDs
Enriched GO Terms of Interacting Partners?
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