PBX3 and CNTRL

		PBX3	CNTRL
Description		PBX homeobox 3	centriolin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Transcription Factor Complex	Centrosome Microtubule Organizing Center Cytosol Membrane Flemming Body Centriolar Subdistal Appendage
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific	Protein Binding Cytoskeletal Protein Binding
	Biological Process	Regulation Of Respiratory Gaseous Exchange By Neurological System Process Anterior Compartment Pattern Formation Posterior Compartment Specification Respiratory Gaseous Exchange Adult Locomotory Behavior Dorsal Spinal Cord Development Positive Regulation Of Transcription By RNA Polymerase II Neuron Development	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Division Regulation Of Cytoskeleton Organization Ciliary Basal Body-plasma Membrane Docking
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Dentures ( 31235808) Medication use (opioids) ( 31015401) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Pulse pressure ( 30578418) Response to mTOR inhibitor (everolimus) ( 24009623) Sleep duration ( 30531941) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 30224653 30578418)	Pulse pressure ( 27841878)
Interacting Genes		15 interacting genes: AGTRAP ARL6IP1 CNTRL FSD2 HOXA9 HOXB8 MAGEA1 MAGEC2 MAL2 MEIS1 RABAC1 TPM3 TRAF1 TRIM44 ZNHIT3	7 interacting genes: ENG MAP3K4 MAPK6 PBX3 SPTAN1 TRADD TRAF1
Entrez ID		5090	11064
HPRD ID		15938	05691
Ensembl ID		ENSG00000167081	ENSG00000119397
Uniprot IDs		P40426 Q5JS98 Q96AL5	B2RP65 Q7Z7A1
PDB IDs
Enriched GO Terms of Interacting Partners?
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