NFE2L1 and MAFF

Number of citations of the paper that reports this interaction (PubMedID 8932385)
26

Data Source:
HPRD (in vitro)

		NFE2L1	MAFF
Description		nuclear factor, erythroid 2 like 1	MAF bZIP transcription factor F
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Cell Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane Protein-containing Complex	Nuclear Chromatin Nucleus Nucleoplasm Mitochondrion
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Coregulator Activity Protein Binding Cholesterol Binding Protein Domain Specific Binding Protein-containing Complex Binding Promoter-specific Chromatin Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Protein Polyubiquitination Fructose 6-phosphate Metabolic Process Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Glutathione Metabolic Process Heme Biosynthetic Process Inflammatory Response Regulation Of Mitotic Nuclear Division Cholesterol Metabolic Process Anatomical Structure Morphogenesis Regulation Of Glucose Metabolic Process Regulation Of Fatty Acid Metabolic Process Cellular Homeostasis Spinal Cord Motor Neuron Differentiation Glial Cell Fate Commitment Erythrocyte Differentiation Cellular Response To Oxidative Stress Response To Endoplasmic Reticulum Stress Cholesterol Homeostasis Cysteine Transport Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Inflammatory Response Glucose 6-phosphate Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Cold Cellular Response To Copper Ion Cellular Response To Cholesterol Regulation Of Nucleus Organization Regulation Of Response To Endoplasmic Reticulum Stress	In Utero Embryonic Development Transcription By RNA Polymerase II Parturition Blood Coagulation Skeletal Muscle Cell Differentiation Regulation Of Epidermal Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs		Lauryl Dimethylamine-N-Oxide
Diseases
GWAS		Generalized epilepsy ( 22949513) Heel bone mineral density ( 30598549)	Birth weight ( 31043758) Estimated glomerular filtration rate ( 31152163 31015462 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) HDL cholesterol ( 30275531) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Height ( 31562340) Triglyceride levels ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglycerides ( 30275531)
Interacting Genes		15 interacting genes: ATF4 BACH2 CAPN1 CD6 CREBZF GSK3B HCFC1 JUN JUNB JUND MAFF MAFG MAFK NFE2L3 PARVA	22 interacting genes: ATF3 BACH2 BATF2 BATF3 DDIT3 FOS GTF2A1L HDAC5 HOXD12 MAFG MAFIP NFE2 NFE2L1 NFE2L2 NFIL3 NR3C1 NRF1 OVOL1 PPARG PRRX1 PSAP SUN2
Entrez ID		4779	23764
HPRD ID		01223	05343
Ensembl ID		ENSG00000082641	ENSG00000185022
Uniprot IDs		J9JIE5 Q14494 Q8NF22	Q9ULX9
PDB IDs
Enriched GO Terms of Interacting Partners?
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