ASNS and TRIM69

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ASNS	TRIM69
Description		asparagine synthetase (glutamine-hydrolyzing)	tripartite motif containing 69
Image
GO Annotations	Cellular Component	Cytosol	Nucleus Cytoplasm Cytosol Nuclear Speck
	Molecular Function	Asparagine Synthase (glutamine-hydrolyzing) Activity Protein Binding ATP Binding Identical Protein Binding Cofactor Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding
	Biological Process	Liver Development Asparagine Biosynthetic Process Glutamine Metabolic Process Cellular Amino Acid Biosynthetic Process Response To Light Stimulus Response To Mechanical Stimulus Response To Toxic Substance Response To Methotrexate Response To Follicle-stimulating Hormone Cellular Response To Hormone Stimulus PERK-mediated Unfolded Protein Response Cellular Response To Glucose Starvation Negative Regulation Of Apoptotic Process Response To Amino Acid Positive Regulation Of Mitotic Cell Cycle L-asparagine Biosynthetic Process	Protein Polyubiquitination Apoptotic Process
Pathways		ATF4 activates genes in response to endoplasmic reticulum stress Aspartate and asparagine metabolism Response of EIF2AK4 (GCN2) to amino acid deficiency Response of EIF2AK1 (HRI) to heme deficiency	Antigen processing: Ubiquitination & Proteasome degradation
Drugs		L-Aspartic Acid Glutamic Acid ATP L-Asparagine
Diseases
GWAS		Regular attendance at a religious group ( 29970889) Tuberculosis ( 30713548)	Estimated glomerular filtration rate in non-diabetics ( 31451708)
Interacting Genes		5 interacting genes: ATXN1 RAB8A STRN4 TRIM69 WDR27	28 interacting genes: APP ASNS ATP5MC1 DVL1 FAM110A FKBP1B HAUS1 HGS IYD KRT17 LARP1B MAGEA4 NEK8 PML PPP1R18 RECK RSPH14 SF1 SF3A3 SKIL SYNE4 TRIM44 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N ZNF483
Entrez ID		440	140691
HPRD ID		00153	11518
Ensembl ID		ENSG00000070669	ENSG00000185880
Uniprot IDs		P08243	H0YL66 Q86WT6
PDB IDs		6GQ3	4NQJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?