TRIM69 and RECK

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		TRIM69	RECK
Description		tripartite motif containing 69	reversion inducing cysteine rich protein with kazal motifs
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Nuclear Speck	Extracellular Region Plasma Membrane Membrane Anchored Component Of Membrane Wnt Signalosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding Metalloendopeptidase Inhibitor Activity Wnt-protein Binding Coreceptor Activity Involved In Canonical Wnt Signaling Pathway
	Biological Process	Protein Polyubiquitination Apoptotic Process	Vasculature Development Blood Vessel Maturation Sprouting Angiogenesis Embryo Implantation Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Negative Regulation Of Cell Migration Embryonic Forelimb Morphogenesis Regulation Of Angiogenesis Canonical Wnt Signaling Pathway Regulation Of Establishment Of Blood-brain Barrier Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Metalloendopeptidase Activity
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Estimated glomerular filtration rate in non-diabetics ( 31451708)	Bipolar disorder (inflammation and infection response interaction) ( 25781172) IgG glycosylation ( 23382691)
Interacting Genes		28 interacting genes: APP ASNS ATP5MC1 DVL1 FAM110A FKBP1B HAUS1 HGS IYD KRT17 LARP1B MAGEA4 NEK8 PML PPP1R18 RECK RSPH14 SF1 SF3A3 SKIL SYNE4 TRIM44 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N ZNF483	15 interacting genes: CEP44 CTH KEAP1 KRT40 MEOX2 MMP9 MTNR1B NOTCH2NLA REL SIGMAR1 TCF4 TEKT4 TRIM39 TRIM69 USHBP1
Entrez ID		140691	8434
HPRD ID		11518	05567
Ensembl ID		ENSG00000185880	ENSG00000122707
Uniprot IDs		H0YL66 Q86WT6	A8K9D8 O95980 Q6P9E2
PDB IDs		4NQJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?