RAB8A and RPH3A

Number of citations of the paper that reports this interaction (PubMedID 12578829)
52

Data Source:
HPRD (in vitro)

		RAB8A	RPH3A
Description		RAB8A, member RAS oncogene family	rabphilin 3A
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endosome Centrosome Centriole Cytosol Plasma Membrane Cilium Synaptic Vesicle Endomembrane System Postsynaptic Density Trans-Golgi Network Transport Vesicle Midbody Phagocytic Vesicle Membrane Trans-Golgi Network Membrane Ciliary Basal Body Neuronal Cell Body Dendritic Spine Phagocytic Vesicle Recycling Endosome Membrane Extracellular Exosome Ciliary Base Non-motile Cilium Glutamatergic Synapse	Golgi Apparatus Cytosol Synaptic Vesicle Extrinsic Component Of Membrane Cell Junction Secretory Granule Synaptic Vesicle Membrane Protein-containing Complex Neuron Projection Dendritic Spine Synapse Postsynaptic Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Rab GTPase Binding GDP Binding Protein Kinase Binding Myosin V Binding	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Zinc Ion Binding Selenium Binding Rab GTPase Binding Phosphate Ion Binding Protein-containing Complex Binding Inositol 1,4,5 Trisphosphate Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Autophagy Axonogenesis Protein Secretion Regulation Of Autophagy Regulation Of Exocytosis Rab Protein Signal Transduction Cellular Response To Insulin Stimulus Post-translational Protein Modification Regulation Of Long-term Neuronal Synaptic Plasticity Golgi Vesicle Fusion To Target Membrane Regulation Of Protein Transport Cilium Assembly Protein Localization To Plasma Membrane Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Vesicle-mediated Transport In Synapse	Intracellular Protein Transport Spontaneous Neurotransmitter Secretion
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular volume ( 27863252) Mean platelet volume ( 27863252)	Alcohol consumption (max-drinks) ( 29460428) Body mass index ( 26426971) Chloride levels ( 29403010) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Low density lipoprotein cholesterol levels ( 29403010) Low HDL-cholesterol levels ( 31006500) Platelet count ( 22139419) Urate levels ( 31578528)
Interacting Genes		34 interacting genes: ASNS BAG6 BIRC6 GDI2 IKBKG JAK3 KCNN1 MALT1 MAP4K2 MDM2 MYO5C MYO9B NR2F6 OCRL ODF2 OPTN PDE6D PQBP1 PRKACA RAB11A RAB13 RAB3IL1 RAB3IP RABIF RIMS2 RPH3A RPH3AL STEAP1 SYTL1 SYTL4 TAS2R9 TFRC TPM4 UGT2B15	10 interacting genes: ADD2 CASK GCH1 NRXN1 RAB15 RAB27A RAB3A RAB3B RAB8A YWHAH
Entrez ID		4218	22895
HPRD ID		01296	15273
Ensembl ID		ENSG00000167461	ENSG00000089169
Uniprot IDs		A0A024R7I3 P61006	A0A024RBK6 Q9Y2J0
PDB IDs		3QBT 3TNF 4LHV 4LHW 4LHX 4LHY 4LHZ 4LI0 5SZI
Enriched GO Terms of Interacting Partners?
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