MCM6 and MLLT3

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		MCM6	MLLT3
Description		minichromosome maintenance complex component 6	MLLT3 super elongation complex subunit
Image
GO Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm MCM Complex	Nucleus Nucleoplasm Chromosome Cytosol Transcription Elongation Factor Complex Extracellular Exosome
	Molecular Function	DNA Helicase Activity DNA Replication Origin Binding Single-stranded DNA Binding Protein Binding ATP Binding Identical Protein Binding Single-stranded DNA-dependent ATP-dependent 3'-5' DNA Helicase Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Histone Binding Lysine-acetylated Histone Binding Modification-dependent Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Double-strand Break Repair Via Break-induced Replication DNA Replication Pre-replicative Complex Assembly Involved In Nuclear Cell Cycle DNA Replication DNA Unwinding Involved In DNA Replication DNA Replication Initiation Mitotic DNA Replication	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Segment Specification Anterior/posterior Pattern Specification Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Pathways		Activation of ATR in response to replication stress Unwinding of DNA Assembly of the pre-replicative complex Orc1 removal from chromatin Activation of the pre-replicative complex Switching of origins to a post-replicative state	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Body mass index ( 25673413) Hip circumference ( 25673412) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)	Atrial fibrillation ( 29892015) Estimated glomerular filtration rate ( 31152163) Response to montelukast in asthma (change in FEV1) ( 26083242) Systolic blood pressure ( 30578418)
Interacting Genes		36 interacting genes: C2CD6 CCNA1 CDC45 CDC7 CDKN2A CDT1 CHEK1 CRLS1 DBF4 ESCO2 FAM161A GMNN HSPB1 IL36RN ING5 MCM10 MCM2 MCM3 MCM4 MCM7 MCM8 MCMBP MLLT3 MTDH NUDT2 ORC1 ORC2 ORC4 ORC6 PSMA1 RPA1 SCNM1 SMC1A SNRPB2 UBE3A ZBTB9	16 interacting genes: AFF1 ALKBH4 APP APPBP2 BCOR CBX8 CDK6 COL6A1 EEF1A1 H3C1 LRIF1 LRRK2 MCM6 PTN RBM48 SGK1
Entrez ID		4175	4300
HPRD ID		03485	01163
Ensembl ID		ENSG00000076003	ENSG00000171843
Uniprot IDs		Q14566	A0A0S2Z448 P42568
PDB IDs		2KLQ 2LE8	2LM0 2MV7 2N4Q 2NDF 2NDG 4TMP 5HJB 5HJD 5YYF 6B7G 6MIL 6MIM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?