MLLT3 and AFF1

  • Number of citations of the paper that reports this interaction (PubMedID 21729782)
  • 142
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro, two hybrid, in vivo)

MLLT3

AFF1

Description MLLT3 super elongation complex subunit AF4/FMR2 family member 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Atrial fibrillation ( 29892015)
  • Estimated glomerular filtration rate ( 31152163)
  • Response to montelukast in asthma (change in FEV1) ( 26083242)
  • Systolic blood pressure ( 30578418)
  • Alzheimer's disease (cognitive decline) ( 23535033)
  • Basophil percentage of granulocytes ( 27863252)
  • Basophil percentage of white cells ( 27863252)
  • Bulimia nervosa ( 23568457)
  • Diastolic blood pressure ( 28234671)
  • Eyebrow thickness ( 26926045)
  • HDL cholesterol levels ( 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Heel bone mineral density ( 30598549 28869591)
  • Hematocrit ( 29403010 27863252)
  • Hemoglobin ( 29403010)
  • Hemoglobin concentration ( 27863252)
  • Mean corpuscular hemoglobin ( 29403010 27863252)
  • Mean corpuscular volume ( 29403010 27863252)
  • Mean platelet volume ( 27863252)
  • Medication use (thyroid preparations) ( 31015401)
  • Metabolic syndrome ( 31589552)
  • Multiple sclerosis ( 31604244)
  • Red blood cell count ( 27863252)
  • Systemic lupus erythematosus ( 22291604)
  • Total bilirubin levels ( 29403010)
  • Triglyceride levels ( 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x long total sleep time interaction (2df test) ( 31719535)
  • Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
  • Triglycerides ( 20864672 30275531 25961943 20686565)
  • White blood cell count (basophil) ( 29403010 27863252)
Interacting Genes 16 interacting genes: AFF1 ALKBH4 APP APPBP2 BCOR CBX8 CDK6 COL6A1 EEF1A1 H3C1 LRIF1 LRRK2 MCM6 PTN RBM48 SGK1 9 interacting genes: H3-4 MLLT1 MLLT3 NT5E SASH1 SIAH1 SIAH2 SMAD9 TBCA
Entrez ID 4300 4299
HPRD ID 01163 08871
Ensembl ID ENSG00000171843 ENSG00000172493
Uniprot IDs A0A0S2Z448 P42568 B4DJU9 P51825 Q14C88
PDB IDs 2LM0 2MV7 2N4Q 2NDF 2NDG 4TMP 5HJB 5HJD 5YYF 6B7G 6MIL 6MIM 2LM0
Enriched GO Terms of Interacting Partners?
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