LAMC2 and SLA2

Number of citations of the paper that reports this interaction (PubMedID 17353186)
11

Data Source:
BioGRID (far western blotting)

		LAMC2	SLA2
Description		laminin subunit gamma 2	Src like adaptor 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Laminin-2 Complex Extracellular Space Cell Cortex Membrane Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix	Nucleoplasm Cytoplasm Late Endosome Golgi Apparatus Plasma Membrane Phosphatidylinositol 3-kinase Complex Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Extracellular Matrix Structural Constituent Heparin Binding	SH3/SH2 Adaptor Activity Protein Binding 1-phosphatidylinositol-3-kinase Regulator Activity Protein N-terminus Binding
	Biological Process	Cell Adhesion Motor Neuron Axon Guidance Positive Regulation Of Cell Proliferation Epidermis Development Animal Organ Morphogenesis Tissue Development Dendrite Development Extracellular Matrix Organization Positive Regulation Of Cell Migration Hemidesmosome Assembly	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Signal Transduction B Cell Mediated Immunity Intracellular Receptor Signaling Pathway T Cell Activation Regulation Of Phosphatidylinositol 3-kinase Activity Phosphatidylinositol Phosphorylation Regulation Of Immune Response Negative Regulation Of Calcium-mediated Signaling Antigen Receptor-mediated Signaling Pathway Negative Regulation Of B Cell Activation
Pathways		Degradation of the extracellular matrix Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Anchoring fibril formation Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions Type I hemidesmosome assembly MET activates PTK2 signaling
Drugs
Diseases		Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
GWAS		Acne (severe) ( 30542056) Blood protein levels ( 30072576 29875488) Clozapine-induced agranulocytosis ( 25187353) HDL cholesterol ( 21347282) Morning person ( 30696823) Systemic lupus erythematosus ( 21408207)
Interacting Genes		8 interacting genes: BMP1 COL7A1 CSF1R FBLN2 LAMB3 NID1 SCAP SLA2	7 interacting genes: CBL CD247 CSF1 EGFR ERBB2 LAMC2 ZAP70
Entrez ID		3918	84174
HPRD ID		01031	05955
Ensembl ID		ENSG00000058085	ENSG00000101082
Uniprot IDs		Q13753	Q9H6Q3
PDB IDs			4M4Z
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
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