KRT17 and TRIM69

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KRT17	TRIM69
Description		keratin 17	tripartite motif containing 69
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Intermediate Filament Cytoskeleton Extracellular Exosome Cell Periphery	Nucleus Cytoplasm Cytosol Nuclear Speck
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding MHC Class II Receptor Activity MHC Class II Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding
	Biological Process	Signal Transduction Epidermis Development Positive Regulation Of Cell Growth Hair Follicle Morphogenesis Keratinization Intermediate Filament Organization Positive Regulation Of Translation Positive Regulation Of Hair Follicle Development Cornification	Protein Polyubiquitination Apoptotic Process
Pathways		Keratinization Formation of the cornified envelope	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS			Estimated glomerular filtration rate in non-diabetics ( 31451708)
Interacting Genes		10 interacting genes: APC CCDC85B EGFR HRAS KDM1A KRT6A KRT7 KRT72 TRIM69 ZDHHC17	28 interacting genes: APP ASNS ATP5MC1 DVL1 FAM110A FKBP1B HAUS1 HGS IYD KRT17 LARP1B MAGEA4 NEK8 PML PPP1R18 RECK RSPH14 SF1 SF3A3 SKIL SYNE4 TRIM44 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N ZNF483
Entrez ID		3872	140691
HPRD ID		01019	11518
Ensembl ID		ENSG00000128422	ENSG00000185880
Uniprot IDs		Q04695 Q14666	H0YL66 Q86WT6
PDB IDs			4NQJ
Enriched GO Terms of Interacting Partners?
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