CXCR2 and ARRB1

  • Number of citations of the paper that reports this interaction (PubMedID 11170396)
  • 39
  • Data Source:
  • HPRD (in vivo)

CXCR2

ARRB1

Description C-X-C motif chemokine receptor 2 arrestin beta 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Granulocyte count ( 27863252)
  • Granulocyte percentage of myeloid white cells ( 27863252)
  • Inflammatory bowel disease ( 28067908 23128233)
  • Lymphocyte percentage of white cells ( 27863252)
  • Monocyte percentage of white cells ( 27863252)
  • Myeloid white cell count ( 27863252)
  • Neutrophil count ( 27863252)
  • Neutrophil percentage of white cells ( 27863252)
  • Smooth-surface caries ( 23470693)
  • Sum basophil neutrophil counts ( 27863252)
  • Sum neutrophil eosinophil counts ( 27863252)
  • White blood cell count ( 27863252)
  • Obstructive sleep apnea trait (average respiratory event duration) ( 26977737)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes 21 interacting genes: ADRA1A ARRB1 CXCL1 CXCL2 CXCL3 CXCL5 CXCL6 CXCL8 CXCR1 GNA14 GNA15 GNAI2 GNAI3 GPRASP1 GRIA1 MYO5B PPBP PPP2CA RAB11FIP2 RGS12 ST13 54 interacting genes: ADH6 ADRB1 ADRB2 AGTR1 AP2B1 ARF6 BAG1 BTK C5AR1 CCR5 CDC42 CLTC CSK CXCR2 CYTH2 DVL1 DVL2 FGR FLNA GNB1 GNMT GPR50 GRK2 GSK3B HCK HCRTR1 JUN LIMK1 MAP2K3 MAP2K4 MAP3K5 MAPK1 MAPK10 MAPK3 MAPK9 MDM2 NEK6 NFKBIA NSF OPRD1 PDE4D PIK3R2 POT1 PRKN PTH1R PTHLH RALGDS RPL15 SASH1 SLC9A5 SREBF2 STAM TRHR ZBTB43
Entrez ID 3579 408
HPRD ID 00907 00146
Ensembl ID ENSG00000180871 ENSG00000137486
Uniprot IDs P25025 Q53PC4 B7Z1Q3 P49407
PDB IDs 4Q3H 5TYT 2IV8
Enriched GO Terms of Interacting Partners?
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