HOXD4 and PBX1

Number of citations of the paper that reports this interaction (PubMedID 10523646)
53

Data Source:
HPRD (in vivo, in vitro)

		HOXD4	PBX1
Description		homeobox D4	PBX homeobox 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cell Junction	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Factor Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Activating Transcription Factor Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Skeletal System Development Multicellular Organism Development Anterior/posterior Pattern Specification Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis	Branching Involved In Ureteric Bud Morphogenesis Steroid Biosynthetic Process Positive Regulation Of Transcription Of Notch Receptor Target Sex Differentiation Positive Regulation Of Cell Proliferation Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Ossification Adrenal Gland Development Embryonic Limb Morphogenesis Somatic Stem Cell Population Maintenance Embryonic Hemopoiesis Negative Regulation Of Neuron Differentiation Spleen Development Thymus Development Embryonic Skeletal System Development
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis	Transcriptional regulation of pluripotent stem cells Activation of anterior HOX genes in hindbrain development during early embryogenesis NOTCH3 Intracellular Domain Regulates Transcription
Drugs
Diseases			Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)
GWAS		Estimated glomerular filtration rate ( 31015462) Male-pattern baldness ( 28196072) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Pelvic organ prolapse (moderate/severe) ( 26545240)	Asthma ( 29273806) Breast cancer (prognosis) ( 23319801) Cough in response to angiotensin-converting enzyme inhibitor drugs ( 28084903) Early-onset Parkinson's disease ( 28256260) Height ( 20966902) Myopia ( 27182965) Night sleep phenotypes ( 27126917) Pre-treatment viral load in HIV-1 infection ( 31219150) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		19 interacting genes: ASB8 CNOT7 CREBBP DEDD EP300 ETV4 HIPK1 HNRNPAB HOXB13 MEIS1 PBX1 RNPS1 RXRG SNAI1 TIGD4 XRCC6 ZBTB32 ZMYND11 ZSCAN18	23 interacting genes: CREBBP HOXA10 HOXA5 HOXA9 HOXB1 HOXB7 HOXB8 HOXD10 HOXD4 HOXD9 KAT2A MDM2 MEIS1 MEIS2 MYH10 NEDD4L NR3C1 PAX6 PBX2 PDX1 PKNOX1 POU2F1 SMARCD3
Entrez ID		3233	5087
HPRD ID		00864	08889
Ensembl ID		ENSG00000170166	ENSG00000185630
Uniprot IDs		P09016	A1MJ41 A8K5V0 P40424 Q53YC7
PDB IDs			1B72 1PUF
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?