OSGIN1 and INCA1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		OSGIN1	INCA1
Description		oxidative stress induced growth inhibitor 1	inhibitor of CDK, cyclin A1 interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component	Nucleus Nucleoplasm Cytoplasm Nuclear Body
	Molecular Function	Protein Binding Growth Factor Activity	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Cyclin Binding Protein-containing Complex Binding
	Biological Process	Signal Transduction Multicellular Organism Development Cell Differentiation Negative Regulation Of Cell Growth Regulation Of Cell Migration Regulation Of Cell Proliferation Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process	Negative Regulation Of Cell Proliferation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		LDL cholesterol ( 30275531) Pursuit maintenance gain ( 29064472) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)	Intraocular pressure ( 29235454) Obesity-related traits ( 23251661)
Interacting Genes		23 interacting genes: AKT1 ATM BCAR3 CAPN3 CCDC33 CRX DNAJA3 FGFR4 IKZF3 INCA1 KRAS LNX1 MEIS2 MEOX2 PPM1D PTEN REL SAXO1 SMARCB1 TCF12 TCF4 TLE5 XRCC3	39 interacting genes: ARMC7 CABP5 CCNA1 CDC23 CDK2 CDKN2D CHCHD2 COL8A1 CTNNBIP1 DAZAP2 DMRT3 DPH7 EPHB6 FHL2 FMR1 GRB2 HAUS1 NEK6 OSGIN1 PATE1 PTGER3 RAB5C RAMAC RBPMS RNF26 SAP18 SCNM1 SEC14L4 SPG21 SPOUT1 STAMBPL1 STK16 TRIM26 TRIP6 UBE2D4 UBXN2B VPS28 ZMYND19 ZNF205-AS1
Entrez ID		29948	388324
HPRD ID		06412	17150
Ensembl ID		ENSG00000140961	ENSG00000196388
Uniprot IDs		Q9UJX0	Q0VD86
PDB IDs
Enriched GO Terms of Interacting Partners?
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