OSGIN1 and BCAR3

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		OSGIN1	BCAR3
Description		oxidative stress induced growth inhibitor 1	BCAR3 adaptor protein, NSP family member
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component
	Molecular Function	Protein Binding Growth Factor Activity	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinase Binding
	Biological Process	Signal Transduction Multicellular Organism Development Cell Differentiation Negative Regulation Of Cell Growth Regulation Of Cell Migration Regulation Of Cell Proliferation Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process	Lens Morphogenesis In Camera-type Eye Signal Transduction Small GTPase Mediated Signal Transduction Insulin Receptor Signaling Pathway Positive Regulation Of Peptidyl-serine Phosphorylation Response To Drug Positive Regulation Of MAPK Cascade Positive Regulation Of GTPase Activity Positive Regulation Of DNA Replication Endothelin Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		LDL cholesterol ( 30275531) Pursuit maintenance gain ( 29064472) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)	Alzheimer's disease progression score ( 29860282) Blood urea nitrogen levels ( 31152163) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Major depressive disorder ( 27777418) Systolic blood pressure ( 30224653)
Interacting Genes		23 interacting genes: AKT1 ATM BCAR3 CAPN3 CCDC33 CRX DNAJA3 FGFR4 IKZF3 INCA1 KRAS LNX1 MEIS2 MEOX2 PPM1D PTEN REL SAXO1 SMARCB1 TCF12 TCF4 TLE5 XRCC3	29 interacting genes: AGR3 APP ATAD2 BAP1 BEX1 BEX2 CASZ1 CCL5 CST6 DKK3 EPSTI1 ERBB2 ERBB3 ERRFI1 GLCE GREB1 HOXC6 KPNA1 MTA3 NEDD9 NSD3 OSGIN1 PDLIM2 PRDM14 PSMC3IP RPRD1A SERPINB5 THRSP VPS45
Entrez ID		29948	8412
HPRD ID		06412	05268
Ensembl ID		ENSG00000140961	ENSG00000137936
Uniprot IDs		Q9UJX0	A0A384MTS3 B3KNL6 B3KP06 O75815
PDB IDs			3T6A
Enriched GO Terms of Interacting Partners?
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