SSU72 and RAD21

Number of citations of the paper that reports this interaction (PubMedID 20818333)
5

Data Source:
BioGRID (affinity chromatography technology, pull down, affinity chromatography technology)

		SSU72	RAD21
Description		SSU72 homolog, RNA polymerase II CTD phosphatase	RAD21 cohesin complex component
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GO Annotations	Cellular Component	Nucleoplasm Cytosol MRNA Cleavage And Polyadenylation Specificity Factor Complex	Chromosome, Centromeric Region Chromatin Nuclear Cohesin Complex Spindle Pole Nucleoplasm Chromosome Cytosol Cohesin Complex Membrane Nuclear Matrix Meiotic Cohesin Complex
	Molecular Function	Protein Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity	Chromatin Binding Protein Binding
	Biological Process	Termination Of RNA Polymerase II Transcription MRNA Polyadenylation Dephosphorylation Of RNA Polymerase II C-terminal Domain	Double-strand Break Repair DNA Recombination Regulation Of Transcription By RNA Polymerase II Apoptotic Process Sister Chromatid Cohesion Reciprocal Meiotic Recombination Multicellular Organism Development Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Sister Chromatid Cohesion Cell Division Meiotic Cell Cycle Protein Localization To Chromatin
Pathways		RNA polymerase II transcribes snRNA genes	Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Menopause (age at onset) ( 29773799)
Interacting Genes		5 interacting genes: GNB1 MAPK8 MAPK9 RAD21 STAG2	28 interacting genes: CAPN1 CASP7 CFL1 CSTB DISC1 DYNLT1 FHL3 FLNB HNRNPH2 IL7R MSRB2 MT-CO2 NUMA1 PPP1R15A PPP1R15B RPL10 RPL13 RPL35A SMARCA5 SMC1A SSU72 STAG1 STAG2 TMSB4X TNFRSF14 WAPL WNT2B ZNF80
Entrez ID		29101	5885
HPRD ID		13712	05924
Ensembl ID		ENSG00000160075	ENSG00000164754
Uniprot IDs		Q9NP77	A0A024R9J0 O60216
PDB IDs		3O2Q 3O2S 4H3H 4H3K	4PJU 4PJW 4PK7 6RRC 6RRK
Enriched GO Terms of Interacting Partners?
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