RAD21 and STAG2

Number of citations of the paper that reports this interaction (PubMedID 26496610)
285

Data Source:
BioGRID (biochemical, affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo)

		RAD21	STAG2
Description		RAD21 cohesin complex component	stromal antigen 2
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nuclear Cohesin Complex Spindle Pole Nucleoplasm Chromosome Cytosol Cohesin Complex Membrane Nuclear Matrix Meiotic Cohesin Complex	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Cytosol Cohesin Complex Membrane Nuclear Matrix Mitotic Spindle Pole
	Molecular Function	Chromatin Binding Protein Binding	Chromatin Binding Protein Binding
	Biological Process	Double-strand Break Repair DNA Recombination Regulation Of Transcription By RNA Polymerase II Apoptotic Process Sister Chromatid Cohesion Reciprocal Meiotic Recombination Multicellular Organism Development Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Sister Chromatid Cohesion Cell Division Meiotic Cell Cycle Protein Localization To Chromatin	Sister Chromatid Cohesion Cell Division Meiotic Cell Cycle Regulation Of Mitotic Spindle Assembly
Pathways		Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression	Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Menopause (age at onset) ( 29773799)
Interacting Genes		28 interacting genes: CAPN1 CASP7 CFL1 CSTB DISC1 DYNLT1 FHL3 FLNB HNRNPH2 IL7R MSRB2 MT-CO2 NUMA1 PPP1R15A PPP1R15B RPL10 RPL13 RPL35A SMARCA5 SMC1A SSU72 STAG1 STAG2 TMSB4X TNFRSF14 WAPL WNT2B ZNF80	4 interacting genes: PLK1 RAD21 SSU72 STAG1
Entrez ID		5885	10735
HPRD ID		05924	05077
Ensembl ID		ENSG00000164754	ENSG00000101972
Uniprot IDs		A0A024R9J0 O60216	Q6AI02 Q6MZM3 Q6MZP3 Q8N3U4
PDB IDs		4PJU 4PJW 4PK7 6RRC 6RRK	4PJU 4PJW 4PK7
Enriched GO Terms of Interacting Partners?
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