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RAD21

Description RAD21 cohesin complex component
Image
GO Annotations Cellular Component
  • Chromosome, Centromeric Region
  • Chromatin
  • Nuclear Cohesin Complex
  • Spindle Pole
  • Nucleoplasm
  • Chromosome
  • Cytosol
  • Cohesin Complex
  • Membrane
  • Nuclear Matrix
  • Meiotic Cohesin Complex
Molecular Function
  • Chromatin Binding
  • Protein Binding
Biological Process
  • Double-strand Break Repair
  • DNA Recombination
  • Regulation Of Transcription By RNA Polymerase II
  • Apoptotic Process
  • Sister Chromatid Cohesion
  • Reciprocal Meiotic Recombination
  • Multicellular Organism Development
  • Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle
  • Negative Regulation Of Mitotic Metaphase/anaphase Transition
  • Positive Regulation Of Sister Chromatid Cohesion
  • Cell Division
  • Meiotic Cell Cycle
  • Protein Localization To Chromatin
Pathways
  • Meiotic synapsis
  • Separation of Sister Chromatids
  • Establishment of Sister Chromatid Cohesion
  • Cohesin Loading onto Chromatin
  • Resolution of Sister Chromatid Cohesion
  • SUMOylation of DNA damage response and repair proteins
  • Estrogen-dependent gene expression
Drugs
Diseases
GWAS
  • Menopause (age at onset) ( 29773799)
Interacting Genes 28 interacting genes: CAPN1 CASP7 CFL1 CSTB DISC1 DYNLT1 FHL3 FLNB HNRNPH2 IL7R MSRB2 MT-CO2 NUMA1 PPP1R15A PPP1R15B RPL10 RPL13 RPL35A SMARCA5 SMC1A SSU72 STAG1 STAG2 TMSB4X TNFRSF14 WAPL WNT2B ZNF80
Entrez ID 5885
HPRD ID 05924
Ensembl ID ENSG00000164754
Uniprot IDs A0A024R9J0 O60216
PDB IDs 4PJU 4PJW 4PK7 6RRC 6RRK
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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