RABGEF1 and TXN2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RABGEF1	TXN2
Description		RAB guanine nucleotide exchange factor 1	thioredoxin 2
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GO Annotations	Cellular Component	Nucleolus Early Endosome Cytosol Early Endosome Membrane Recycling Endosome	Cell Nucleolus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Rab Guanyl-nucleotide Exchange Factor Activity Rab GTPase Binding	Protein Binding Peptide-methionine (S)-S-oxide Reductase Activity Protein Disulfide Oxidoreductase Activity Peptide-methionine (R)-S-oxide Reductase Activity Protein-containing Complex Binding
	Biological Process	Protein Targeting To Membrane Endocytosis	Sulfur Amino Acid Catabolic Process Response To Hypoxia Glycerol Ether Metabolic Process Response To Oxidative Stress Response To Hormone Response To Glucose Response To Organic Cyclic Compound Cellular Response To Nutrient Levels Response To Drug Cell Redox Homeostasis Response To Axon Injury Oxidation-reduction Process
Pathways		TBC/RABGAPs RAB GEFs exchange GTP for GDP on RABs	Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Aortic root size ( 21223598) Central corneal thickness ( 29760442)
Interacting Genes		29 interacting genes: AP1G1 BLOC1S6 CIPC DAZAP2 DGCR6 DNAJC5 GGA1 GGA2 HRAS KXD1 MON1A MON1B RAB33B RAB4A RABEP1 RNF11 RNF168 RPS27A TEAD4 THOC1 TRIM15 TRIM54 TXN2 UBB UBC UBE2D1 UBE2D3 YWHAB ZC2HC1C	35 interacting genes: AGTRAP ALDOB AP2B1 CCDC114 DCTD FAM9B GPRASP2 KRT18 KRT40 MAGEA11 MAPRE2 MAPRE3 MLH1 MRFAP1L1 MTUS2 PPCDC PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SCYL3 SHARPIN SSNA1 STUB1 SUN2 THAP1 TIFA TRIM21 TRIP6 UCHL5 VIM VPS52 ZBTB14
Entrez ID		27342	25828
HPRD ID		11477	07161
Ensembl ID		ENSG00000154710	ENSG00000100348
Uniprot IDs		A0A024RDL6 A0A0A0MSJ3 A8K3R3 B3KMF1 Q9UJ41	B4DX69 Q99757
PDB IDs		1TXU 2C7M 2C7N 2OT3 4N3X 4N3Y 4N3Z 4Q9U	1UVZ 1W4V 1W89
Enriched GO Terms of Interacting Partners?
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