TXN2 and MAPRE2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TXN2	MAPRE2
Description		thioredoxin 2	microtubule associated protein RP/EB family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Cell Nucleolus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body	Cytoplasm Microtubule Organizing Center Microtubule Cytoplasmic Microtubule Focal Adhesion Microtubule Cytoskeleton Microtubule Plus-end Spindle Midzone
	Molecular Function	Protein Binding Peptide-methionine (S)-S-oxide Reductase Activity Protein Disulfide Oxidoreductase Activity Peptide-methionine (R)-S-oxide Reductase Activity Protein-containing Complex Binding	Protein Binding Microtubule Binding Protein Kinase Binding Identical Protein Binding Microtubule Plus-end Binding
	Biological Process	Sulfur Amino Acid Catabolic Process Response To Hypoxia Glycerol Ether Metabolic Process Response To Oxidative Stress Response To Hormone Response To Glucose Response To Organic Cyclic Compound Cellular Response To Nutrient Levels Response To Drug Cell Redox Homeostasis Response To Axon Injury Oxidation-reduction Process	Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of ARF Protein Signal Transduction Protein Localization To Microtubule Positive Regulation Of GTPase Activity Spindle Assembly Cell Division Positive Regulation Of Keratinocyte Migration Positive Regulation Of Focal Adhesion Disassembly Protein Localization To Microtubule Plus-end
Pathways		Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS			Cerebrospinal fluid AB1-42 levels ( 26252872) Facial morphology ( 29921221) Metabolite levels ( 23823483)
Interacting Genes		35 interacting genes: AGTRAP ALDOB AP2B1 CCDC114 DCTD FAM9B GPRASP2 KRT18 KRT40 MAGEA11 MAPRE2 MAPRE3 MLH1 MRFAP1L1 MTUS2 PPCDC PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SCYL3 SHARPIN SSNA1 STUB1 SUN2 THAP1 TIFA TRIM21 TRIP6 UCHL5 VIM VPS52 ZBTB14	24 interacting genes: APC APP AURKA AURKB CASK CDK2 CDK4 CLASP2 CLIP1 FBXO7 GTSE1 LMNA LMO2 MAPRE1 MAPRE3 NIF3L1 PAXIP1 RBM10 RBM6 SLAIN2 TRAF1 TRAIP TXN2 UBC
Entrez ID		25828	10982
HPRD ID		07161	16157
Ensembl ID		ENSG00000100348	ENSG00000166974
Uniprot IDs		B4DX69 Q99757	A0A024RC33 Q15555
PDB IDs		1UVZ 1W4V 1W89
Enriched GO Terms of Interacting Partners?
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