TXN2 and ALDOB

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		TXN2	ALDOB
Description		thioredoxin 2	aldolase, fructose-bisphosphate B
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GO Annotations	Cellular Component	Cell Nucleolus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body	Microtubule Organizing Center Cytosol Centriolar Satellite Extracellular Exosome
	Molecular Function	Protein Binding Peptide-methionine (S)-S-oxide Reductase Activity Protein Disulfide Oxidoreductase Activity Peptide-methionine (R)-S-oxide Reductase Activity Protein-containing Complex Binding	Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Identical Protein Binding ATPase Binding Fructose-1-phosphate Aldolase Activity Fructose Binding
	Biological Process	Sulfur Amino Acid Catabolic Process Response To Hypoxia Glycerol Ether Metabolic Process Response To Oxidative Stress Response To Hormone Response To Glucose Response To Organic Cyclic Compound Cellular Response To Nutrient Levels Response To Drug Cell Redox Homeostasis Response To Axon Injury Oxidation-reduction Process	Fructose Metabolic Process Gluconeogenesis Glycolytic Process NADH Oxidation Fructose 1,6-bisphosphate Metabolic Process Positive Regulation Of ATPase Activity Canonical Glycolysis Fructose Catabolic Process To Hydroxyacetone Phosphate And Glyceraldehyde-3-phosphate Vacuolar Proton-transporting V-type ATPase Complex Assembly
Pathways		Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species	Hereditary fructose intolerance Glycolysis Gluconeogenesis Fructose catabolism
Drugs			1,6-Fructose Diphosphate (Linear Form) 3-Phosphoglycerol Dihydroxyacetone phosphate
Diseases			Hereditary fructose intolerance; Fructosemia
GWAS			Age-related cataracts ( 25352737) Liver enzyme levels (alkaline phosphatase) ( 22001757) Serum alkaline phosphatase levels ( 29403010)
Interacting Genes		35 interacting genes: AGTRAP ALDOB AP2B1 CCDC114 DCTD FAM9B GPRASP2 KRT18 KRT40 MAGEA11 MAPRE2 MAPRE3 MLH1 MRFAP1L1 MTUS2 PPCDC PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SCYL3 SHARPIN SSNA1 STUB1 SUN2 THAP1 TIFA TRIM21 TRIP6 UCHL5 VIM VPS52 ZBTB14	8 interacting genes: AGXT2 ALDOA APP ATP6V1E1 HIVEP1 HSPA8 MUC20 TXN2
Entrez ID		25828	229
HPRD ID		07161	01972
Ensembl ID		ENSG00000100348	ENSG00000136872
Uniprot IDs		B4DX69 Q99757	A0A024R145 P05062
PDB IDs		1UVZ 1W4V 1W89	1QO5 1XDL 1XDM
Enriched GO Terms of Interacting Partners?
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