SAMM50 and CHCHD3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SAMM50	CHCHD3
Description		SAMM50 sorting and assembly machinery component	coiled-coil-helix-coiled-coil-helix domain containing 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Sorting And Assembly Machinery Complex Mitochondrion Mitochondrial Outer Membrane Integral Component Of Membrane Extracellular Exosome	Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane MICOS Complex Extracellular Exosome
	Molecular Function	Protein Binding	DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Phosphatase Binding Molecular Adaptor Activity
	Biological Process	Mitochondrial Respiratory Chain Complex Assembly Cellular Protein-containing Complex Assembly Cristae Formation Protein Import Into Mitochondrial Outer Membrane Protein-containing Complex Assembly	Negative Regulation Of Transcription By RNA Polymerase II Inner Mitochondrial Membrane Organization Mitochondrial Fusion Cristae Formation
Pathways		Mitochondrial protein import Cristae formation	Mitochondrial protein import Cristae formation
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 30718733) Cholesterol, total ( 26780889) Hematological and biochemical traits ( 20139978) Liver enzyme levels ( 18940312) Liver enzyme levels (alanine transaminase) ( 22001757) Metabolite levels ( 23823483) Nonalcoholic fatty liver disease ( 22719876 29271184 29385134) Nonalcoholic steatohepatitis-derived hepatocellular carcinoma ( 29385134) Pediatric non-alcoholic fatty liver disease activity score ( 23535911) Total cholesterol levels ( 28334899) Type 2 diabetes ( 30054458)	Chronotype ( 30696823) Food allergy ( 29030101) Intercellular adhesion molecule 1 (red blood cell fatty acid level interaction) ( 28820441) Metabolite levels ( 23823483) Peanut allergy ( 29030101) Smoking status (ever vs never smokers) ( 30643258) Urinary potassium excretion ( 31409800)
Interacting Genes		4 interacting genes: CHCHD3 HMGB2 MEOX2 TOMM40	24 interacting genes: AASS AMOTL2 BLZF1 CALCOCO2 CBY2 CCDC33 CCDC85B FANCL GMCL2 GOLGA2 KRT40 KRTAP4-12 LZTS2 NOTCH2NLA NUDT3 PDE4DIP RAB3IP RPGRIP1 SAMM50 SPAG5 SSX2IP TRAF1 TRIM27 USHBP1
Entrez ID		25813	54927
HPRD ID		10826	13044
Ensembl ID		ENSG00000100347	ENSG00000106554
Uniprot IDs		Q9Y512	A4D1N4 B7Z1X9 C9JRZ6 Q9NX63
PDB IDs
Enriched GO Terms of Interacting Partners?
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