TRIM2 and CDK20

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		TRIM2	CDK20
Description		tripartite motif containing 2	cyclin dependent kinase 20
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cilium
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Protein Polyubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Neuron Apoptotic Process	Protein Phosphorylation Cell Cycle Multicellular Organism Development Cell Division Regulation Of Cell Cycle
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		HDL cholesterol ( 30275531) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Heel bone mineral density ( 30598549) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Multiple sclerosis ( 21654844)
Interacting Genes		25 interacting genes: BCL2L11 CDK20 CIB3 DTNBP1 GJB5 LRRC8E MNAT1 MYO5A OTUB2 SIRPA TNFAIP3 TNIK TRIM8 UBAC1 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2U UBE2W	9 interacting genes: CCNH CDK2 CILK1 CSNK2B GTF2IRD1 GTF2IRD2 PANK4 PPP5C TRIM2
Entrez ID		23321	23552
HPRD ID		10279	13010
Ensembl ID		ENSG00000109654	ENSG00000156345
Uniprot IDs		Q9C040	A0A0S2Z562 A0A0S2Z5B6 Q8IZL9
PDB IDs
Enriched GO Terms of Interacting Partners?
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