TRIM2 and CIB3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIM2	CIB3
Description		tripartite motif containing 2	calcium and integrin binding family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Magnesium Ion Binding Calcium Ion Binding Protein Binding
	Biological Process	Protein Polyubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Neuron Apoptotic Process
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		HDL cholesterol ( 30275531) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Heel bone mineral density ( 30598549) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Multiple sclerosis ( 21654844)
Interacting Genes		25 interacting genes: BCL2L11 CDK20 CIB3 DTNBP1 GJB5 LRRC8E MNAT1 MYO5A OTUB2 SIRPA TNFAIP3 TNIK TRIM8 UBAC1 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2U UBE2W	16 interacting genes: BEND7 ENOX2 GMCL1 KASH5 KLF17 LNX1 MEOX1 MEOX2 REL SERTAD1 SP4 TACC3 TLE5 TRIM2 ZNF398 ZNF426
Entrez ID		23321	117286
HPRD ID		10279	16713
Ensembl ID		ENSG00000109654	ENSG00000141977
Uniprot IDs		Q9C040	Q96Q77
PDB IDs
Enriched GO Terms of Interacting Partners?
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