RAB6A and RAB7A

Number of citations of the paper that reports this interaction (PubMedID 10329441)
20

Data Source:
BioGRID (two hybrid)

		RAB6A	RAB7A
Description		RAB6A, member RAS oncogene family	RAB7A, member RAS oncogene family
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Secretory Granule Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Extracellular Exosome Endosome To Plasma Membrane Transport Vesicle	Autophagosome Membrane Cell Lysosome Lysosomal Membrane Late Endosome Golgi Apparatus Lipid Droplet Cytosol Plasma Membrane Endosome Membrane Endomembrane System Secretory Granule Membrane Phagocytic Vesicle Membrane Retromer Complex Late Endosome Membrane Extrinsic Component Of Lysosome Membrane Melanosome Membrane Phagophore Assembly Site Membrane Phagocytic Vesicle Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Domain Specific Binding Myosin V Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Retromer Complex Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Viral Process Peptidyl-cysteine Methylation Antigen Processing And Presentation Rab Protein Signal Transduction Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Neutrophil Degranulation Minus-end-directed Organelle Transport Along Microtubule	Autophagosome Assembly Protein Targeting To Lysosome Intracellular Protein Transport Endocytosis Epidermal Growth Factor Catabolic Process Endosome To Lysosome Transport Protein Transport Lipid Catabolic Process Viral Release From Host Cell Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Protein To Membrane Docking Rab Protein Signal Transduction Retrograde Transport, Endosome To Golgi Neutrophil Degranulation Early Endosome To Late Endosome Transport Positive Regulation Of Protein Catabolic Process Positive Regulation Of Viral Process Establishment Of Vesicle Localization Lipophagy Phagosome Maturation Phagosome Acidification Phagosome-lysosome Fusion Negative Regulation Of Exosomal Secretion Positive Regulation Of Exosomal Secretion Negative Regulation Of Intralumenal Vesicle Formation
Pathways		Pre-NOTCH Processing in Golgi Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	MHC class II antigen presentation Neutrophil degranulation TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs Prevention of phagosomal-lysosomal fusion Suppression of autophagy
Drugs			Guanosine-5'-Diphosphate
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Dimensional psychopathology (Cognitive) ( 29496196) Obesity-related traits ( 23251661)	Body fat mass ( 28552196) Facial morphology traits (63 three-dimensional facial segments) ( 29459680)
Interacting Genes		21 interacting genes: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 GORAB KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SYTL5 TMF1	35 interacting genes: CHM COPG1 ENOPH1 FABP6 GP9 H1-10 KRTAP10-3 KRTAP10-9 PPP2R1A PPP2R1B PRKN RAB13 RAB17 RAB22A RAB4A RAB4B RAB6A RABAC1 RABGGTB RILP RNF115 RPN1 SLC2A4 SNX3 TMCC1 TP53 UCHL5 VPS11 VPS16 VPS18 VPS26A VPS29 VPS39 VPS41 ZHX2
Entrez ID		5870	7879
HPRD ID		01543	03805
Ensembl ID		ENSG00000175582	ENSG00000075785
Uniprot IDs		A0A024R5H8 A0A024R5J5 P20340 Q53ET8	A0A158RFU6 P51149
PDB IDs		1YZQ 2GIL 3BBP 3CWZ 4DKX 5LEF	1T91 1YHN 3LAW 6IYB
Enriched GO Terms of Interacting Partners?
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