Wiki-CORONA
About
Search
Browse
Data Sources
People
Funding
Advanced Search
F2RL1 and CTSG
Number of citations of the paper that reports this interaction (PubMedID
10978167
)
21
Data Source:
HPRD
(in vitro)
F2RL1
CTSG
Description
F2R like trypsin receptor 1
cathepsin G
Image
GO Annotations
Cellular Component
Cell
Early Endosome
Golgi Apparatus
Plasma Membrane
Integral Component Of Plasma Membrane
Pseudopodium
Extracellular Region
Extracellular Space
Nucleus
Cytoplasm
Plasma Membrane
Cell Surface
Cytoplasmic Stress Granule
Secretory Granule
Azurophil Granule Lumen
Collagen-containing Extracellular Matrix
Extracellular Exosome
Molecular Function
G-protein Alpha-subunit Binding
G Protein-coupled Receptor Activity
Signaling Receptor Binding
Protein Binding
Thrombin-activated Receptor Activity
G-protein Beta-subunit Binding
Signaling Receptor Activity
Serine-type Endopeptidase Activity
Protein Binding
Heparin Binding
Peptidase Activity
Serine-type Peptidase Activity
Biological Process
T Cell Activation Involved In Immune Response
Positive Regulation Of Leukocyte Chemotaxis
Positive Regulation Of Cytokine Secretion Involved In Immune Response
Positive Regulation Of Glomerular Filtration
Inflammatory Response
G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Blood Coagulation
Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Blood Coagulation
Positive Regulation Of Cell Migration
Positive Regulation Of Actin Filament Depolymerization
Positive Regulation Of Pseudopodium Assembly
Positive Regulation Of Superoxide Anion Generation
Positive Regulation Of Toll-like Receptor 2 Signaling Pathway
Negative Regulation Of Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of Rho Protein Signal Transduction
Chemokine (C-C Motif) Ligand 2 Secretion
Neutrophil Activation
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Eosinophil Degranulation
Positive Regulation Of GTPase Activity
Innate Immune Response
Cell-cell Junction Maintenance
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of JNK Cascade
Negative Regulation Of JNK Cascade
Positive Regulation Of JNK Cascade
Interleukin-1 Beta Secretion
Leukocyte Migration
Positive Regulation Of Chemotaxis
Positive Regulation Of Positive Chemotaxis
Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway
Defense Response To Virus
Positive Regulation Of Phagocytosis, Engulfment
Establishment Of Endothelial Barrier
Positive Regulation Of ERK1 And ERK2 Cascade
Thrombin-activated Receptor Signaling Pathway
Leukocyte Proliferation
Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium
Interleukin-10 Secretion
Interferon-gamma Secretion
Chemokine Secretion
Negative Regulation Of Chemokine Secretion
Mature Conventional Dendritic Cell Differentiation
Positive Regulation Of Blood Vessel Diameter
Positive Regulation Of Renin Secretion Into Blood Stream
Positive Regulation Of Interleukin-8 Secretion
Positive Regulation Of Interleukin-6 Secretion
Angiotensin Maturation
Protein Phosphorylation
Proteolysis
Immune Response
Antimicrobial Humoral Response
Antibacterial Humoral Response
Extracellular Matrix Disassembly
Neutrophil Degranulation
Cellular Protein Metabolic Process
Positive Regulation Of Immune Response
Defense Response To Gram-negative Bacterium
Defense Response To Fungus
Neutrophil Mediated Killing Of Gram-positive Bacterium
Cellular Response To Lipopolysaccharide
Pathways
Peptide ligand-binding receptors
G alpha (q) signalling events
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Metabolism of Angiotensinogen to Angiotensins
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Interleukin-1 processing
Neutrophil degranulation
Antimicrobial peptides
Suppression of apoptosis
Purinergic signaling in leishmaniasis infection
Drugs
Bis-Napthyl Beta-Ketophosphonic Acid
2-[3-({Methyl[1-(2-Naphthoyl)Piperidin-4-Yl]Amino}Carbonyl)-2-Naphthyl]-1-(1-Naphthyl)-2-Oxoethylphosphonic Acid
Diseases
GWAS
Serum bilirubin levels x sex interaction in metabolic syndrome (
30621171
)
Congenital heart disease (maternal effect) (
28468790
)
Conotruncal heart defects (maternal effects) (
28468790
)
Interacting Genes
21 interacting genes:
ANKRA2
CAPN1
CAPN2
CBL
COPS5
CTSG
CYFIP2
DNMT3L
ELANE
F2
F2R
GPRASP1
JMY
LMNA
MAP1B
NUMA1
PCBD2
PLG
PRTN3
RAD17
ST14
28 interacting genes:
AGT
C3
CAMP
CASP7
CXCL12
CXCR4
ERBIN
F2R
F2RL1
F2RL2
F5
GP1BA
IGFBP3
KNG1
KRT31
LRP1
NOTCH2NLA
PARP1
PPBP
SDC1
SELPLG
SERPINA1
SERPINA3
SERPINB13
SERPINB4
SERPIND1
THBS1
VCAM1
Entrez ID
2150
1511
HPRD ID
02960
00289
Ensembl ID
ENSG00000164251
ENSG00000100448
Uniprot IDs
P55085
P08311
PDB IDs
5NDD
5NDZ
5NJ6
1AU8
1CGH
1KYN
1T32
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?