CTSG and CXCL12

  • Number of citations of the paper that reports this interaction (PubMedID 11241273)
  • 45
  • Data Source:
  • HPRD (in vivo, in vitro)

CTSG

CXCL12

Description cathepsin G C-X-C motif chemokine ligand 12
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Congenital heart disease (maternal effect) ( 28468790)
  • Conotruncal heart defects (maternal effects) ( 28468790)
  • Blood protein levels ( 30072576)
  • Body mass index ( 25760438)
  • Coronary artery disease ( 26708285 24262325 26343387)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Coronary heart disease ( 17634449 21378990)
  • Diastolic blood pressure ( 27841878)
  • Granulocyte count ( 27863252)
  • Left superior temporal gyrus thickness (schizophrenia interaction) ( 26249676)
  • Monocyte count ( 27863252)
  • Myeloid white cell count ( 27863252)
  • Myocardial infarction ( 26343387)
  • Myocardial infarction (early onset) ( 19198609)
  • Neutrophil count ( 27863252)
  • QT interval (ambient particulate matter interaction) ( 28749367)
  • Resistance to Mycobacterium tuberculosis in HIV-positive individuals measured by a negative tuberculin skin test (continuous) ( 28628665)
  • Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)
  • Schizophrenia ( 23212062)
  • Smoking initiation (ever regular vs never regular) ( 31089300)
  • Sum basophil neutrophil counts ( 27863252)
  • Sum neutrophil eosinophil counts ( 27863252)
  • White blood cell count ( 27863252)
Interacting Genes 28 interacting genes: AGT C3 CAMP CASP7 CXCL12 CXCR4 ERBIN F2R F2RL1 F2RL2 F5 GP1BA IGFBP3 KNG1 KRT31 LRP1 NOTCH2NLA PARP1 PPBP SDC1 SELPLG SERPINA1 SERPINA3 SERPINB13 SERPINB4 SERPIND1 THBS1 VCAM1 11 interacting genes: CD4 CTSG CXCR4 DAZAP2 DPP4 ELANE FBXO7 FN1 MMP2 PF4 VCAN
Entrez ID 1511 6387
HPRD ID 00289 02904
Ensembl ID ENSG00000100448 ENSG00000107562
Uniprot IDs P08311 P48061
PDB IDs 1AU8 1CGH 1KYN 1T32 1A15 1QG7 1SDF 1VMC 2J7Z 2K01 2K03 2K04 2K05 2KEC 2KED 2KEE 2KOL 2N55 2NWG 2SDF 3GV3 3HP3 4LMQ 4UAI
Enriched GO Terms of Interacting Partners?
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