AHR and SP1

  • Number of citations of the paper that reports this interaction (PubMedID 10471301)
  • 13

AHR

SP1

Description aryl hydrocarbon receptor Sp1 transcription factor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
  • Bitter beverage consumption ( 31046077)
  • Bitter non-alcoholic beverage consumption ( 31046077)
  • Blood metabolite levels ( 24816252)
  • Caffeine consumption ( 21490707)
  • Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level) ( 27702941)
  • Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941)
  • Coffee consumption ( 31345160 21357676 29367735 31046077 25288136)
  • Coffee consumption (cups per day) ( 25288136)
  • Cutaneous squamous cell carcinoma ( 27424798)
  • Estimated glomerular filtration rate ( 31152163)
  • Inflammatory bowel disease ( 26192919)
  • Lung cancer in ever smokers ( 28604730)
  • Metabolic traits ( 21886157)
  • Microalbuminuria ( 31511532)
  • Plasma kynurenine levels in major depressive disorder ( 29317604)
  • Rosacea symptom severity ( 29771307)
  • Severe influenza A (H1N1) infection ( 26379185)
  • Sweet beverage consumption ( 31046077)
  • Tea consumption ( 31046077)
  • Ulcerative colitis ( 26192919)
  • Urinary albumin excretion ( 30220432)
  • Urinary albumin excretion (no hypertensive medication) ( 30220432)
  • Urinary albumin-to-creatinine ratio ( 31630189 30910378 31511532)
  • Urinary potassium excretion ( 31409800)
  • Urinary sodium excretion ( 31409800)
  • Hypospadias (moderate to severe) ( 31856834)
  • Mean corpuscular hemoglobin ( 29403010)
  • Mean corpuscular volume ( 29403010)
  • Neutrophil percentage of white cells ( 27863252)
  • Parkinsonism in frontotemporal lobe dementia ( 29724592)
  • Percentage gas trapping ( 26030696)
  • Progressive supranuclear palsy ( 30089514)
  • Red blood cell count ( 27863252)
  • Reticulocyte count ( 27863252)
Interacting Genes 35 interacting genes: AIP AR ARNT ARNT2 ARNTL BRCA1 CCNT1 CUL4B DAP3 EP300 ESR1 GTF2F1 GTF2F2 HSP90AA1 IVNS1ABP NCOA1 NCOA2 NCOA7 NCOR2 NEDD8 NR2F1 NRIP1 PTGES3 RB1 RELA SMARCA4 SP1 STUB1 TAF4 TAF6 TAF7 TAF9 TBL3 TBP XPO1 145 interacting genes: AATF AHR AKT1 AR ARHGAP21 ARNT ATF7IP ATF7IP2 BCL11B BCL6 BCOR BRCA1 CASP3 CASP6 CASP7 CBX5 CCNA1 CCNA2 CCND1 CD2 CDK1 CDK2 CEBPB CSNK2A1 CTCFL CTNNB1 DDX5 DROSHA E2F1 E2F2 E2F3 EGR1 ELF1 EP300 ESR1 ESR2 ESRRA ESRRB ESRRG ETS1 GABPA GATA1 GATA3 GATA4 HBZ HCFC1 HDAC1 HDAC2 HIF1A HINT1 HLTF HMGA1 HNF4A HOXC11 HSPA8 HTT IL1B JUN KIF1A KLF10 KLF4 KLF6 LDB1 LMO2 MAPK1 MAPK3 MAPK8 MBD1 MEF2C MEF2D MIER1 MIS18BP1 MSX1 MTREX MYC MYCN MYOD1 MYOG NAP1L1 NCOR1 NCOR2 NEPRO NFKB1 NFKB2 NFYA NFYB NFYC NKX3-1 NOS3 NPM1 NR2F1 NR5A1 NUP62 OGT PARP1 PER3 PML POGZ POU2F1 PPIG PPP1R13L PRKCZ PRKDC PSIP1 PSMC5 PURA RARA RB1 RBBP4 RBL1 REL RELA RNF4 RORA RXRA SENP6 SF3A1 SHC1 SMAD2 SMAD3 SMAD4 SMARCC1 SMARCC2 SOX10 SOX8 SP3 SP4 SREBF1 SREBF2 SRF SUB1 TAF4 TAL1 TBP TLX3 TP53 TP73 TPI1 USP39 VEGFA VHL YY1 ZBTB16 ZBTB2 ZBTB7A
Entrez ID 196 6667
HPRD ID 02596 01796
Ensembl ID ENSG00000106546 ENSG00000185591
Uniprot IDs A0A024R9Z8 P35869 P08047
PDB IDs 5NJ8 1SP1 1SP2 1VA1 1VA2 1VA3
Enriched GO Terms of Interacting Partners?
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