AHR and NEDD8

  • Number of citations of the paper that reports this interaction (PubMedID 12215427)
  • 5
  • Data Source:
  • HPRD (in vitro, in vivo)

AHR

NEDD8

Description aryl hydrocarbon receptor NEDD8 ubiquitin like modifier
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
  • Bitter beverage consumption ( 31046077)
  • Bitter non-alcoholic beverage consumption ( 31046077)
  • Blood metabolite levels ( 24816252)
  • Caffeine consumption ( 21490707)
  • Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level) ( 27702941)
  • Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941)
  • Coffee consumption ( 31345160 21357676 29367735 31046077 25288136)
  • Coffee consumption (cups per day) ( 25288136)
  • Cutaneous squamous cell carcinoma ( 27424798)
  • Estimated glomerular filtration rate ( 31152163)
  • Inflammatory bowel disease ( 26192919)
  • Lung cancer in ever smokers ( 28604730)
  • Metabolic traits ( 21886157)
  • Microalbuminuria ( 31511532)
  • Plasma kynurenine levels in major depressive disorder ( 29317604)
  • Rosacea symptom severity ( 29771307)
  • Severe influenza A (H1N1) infection ( 26379185)
  • Sweet beverage consumption ( 31046077)
  • Tea consumption ( 31046077)
  • Ulcerative colitis ( 26192919)
  • Urinary albumin excretion ( 30220432)
  • Urinary albumin excretion (no hypertensive medication) ( 30220432)
  • Urinary albumin-to-creatinine ratio ( 31630189 30910378 31511532)
  • Urinary potassium excretion ( 31409800)
  • Urinary sodium excretion ( 31409800)
  • Mean corpuscular volume ( 29403010)
  • Systolic blood pressure (cigarette smoking interaction) ( 26752167)
Interacting Genes 35 interacting genes: AIP AR ARNT ARNT2 ARNTL BRCA1 CCNT1 CUL4B DAP3 EP300 ESR1 GTF2F1 GTF2F2 HSP90AA1 IVNS1ABP NCOA1 NCOA2 NCOA7 NCOR2 NEDD8 NR2F1 NRIP1 PTGES3 RB1 RELA SMARCA4 SP1 STUB1 TAF4 TAF6 TAF7 TAF9 TBL3 TBP XPO1 42 interacting genes: AHR ARIH2 ATE1 ATXN3 CBLB CDC34 COPS5 COPS6 CTRC CUL1 CUL2 CUL3 CUL4B DNMT3B GARS1 GHR HGS HIF1A N4BP1 NAE1 NUB1 OTUB1 OTUD5 PARP1 POLI PSMA6 PSMD4 PTK2 RAD23A SENP8 SMURF1 TP53 UBA2 UBA3 UBE2K UBE2M UBL7 UBQLN1 UBXN7 UCHL1 UCHL3 YAF2
Entrez ID 196 4738
HPRD ID 02596 04412
Ensembl ID ENSG00000106546 ENSG00000129559
Uniprot IDs A0A024R9Z8 P35869 Q15843
PDB IDs 5NJ8 1NDD 1R4M 1R4N 1XT9 2BKR 2KO3 2N7K 2NVU 3DBH 3DBL 3DBR 3DQV 3GZN 4F8C 4FBJ 4HCP 4P5O 6R7F
Enriched GO Terms of Interacting Partners?
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