KLC3 and DTX2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KLC3	DTX2
Description		kinesin light chain 3	deltex E3 ubiquitin ligase 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Kinesin Complex Microtubule Motile Cilium Ciliary Rootlet Neuron Projection	Nucleoplasm Cytoplasm Nuclear Membrane
	Molecular Function	Microtubule Motor Activity Protein Binding Microtubule Binding Kinesin Binding	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Axo-dendritic Transport	Notch Signaling Pathway Protein Ubiquitination
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins	Activated NOTCH1 Transmits Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971)
Interacting Genes		37 interacting genes: ABI3 BBS5 BICDL2 CBY2 CCNH CENPP CEP57L1 CROCC DTX2 GEM IHO1 IMP3 KDM1A KIF5A KIF5B KIF5C KRT13 KRT15 MBIP NDC80 NECAB2 NEFL PDE4DIP QARS1 SMARCB1 SNAP47 STX11 TCF4 TSNAX USHBP1 VPS52 WAC YWHAG YWHAH YWHAQ ZNF417 ZNF572	44 interacting genes: ABHD16A ALKBH4 ARNT2 C1orf94 COQ8A DTX1 DTX3 EIF4ENIF1 FAM168A FHL2 GLYCTK GOLGA2 HDC HPCAL1 HPCAL4 KLC3 KRTAP26-1 MDC1 NCALD NCS1 NOTCH1 PLEKHF2 PLSCR1 QARS1 RBPMS RFX6 RHOXF2 RIMBP3 RUNX1 SEC22A SEC23B SPAG8 SPG21 STX12 SUMO1 TRIM54 TRIP13 TRIP6 UBE2D1 UBE2D3 UBE2D4 UBQLN4 VSNL1 ZNF641
Entrez ID		147700	113878
HPRD ID		03212	16841
Ensembl ID		ENSG00000104892	ENSG00000091073
Uniprot IDs		A0A024R0V3 Q6P597	Q86UW9
PDB IDs			6IR0
Enriched GO Terms of Interacting Partners?
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