KLC3 and KIF5A

Number of citations of the paper that reports this interaction (PubMedID 10491391)
42

Data Source:
HPRD (in vivo)

		KLC3	KIF5A
Description		kinesin light chain 3	kinesin family member 5A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Kinesin Complex Microtubule Motile Cilium Ciliary Rootlet Neuron Projection	Cell Cytosol Kinesin Complex Microtubule Membrane Dendrite Cytoplasm Ciliary Rootlet Perikaryon Synapse Perinuclear Region Of Cytoplasm Axon Cytoplasm
	Molecular Function	Microtubule Motor Activity Protein Binding Microtubule Binding Kinesin Binding	Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Kinesin Binding
	Biological Process	Axo-dendritic Transport	Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Movement Chemical Synaptic Transmission Axon Guidance Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cytoskeleton-dependent Intracellular Transport Synaptic Vesicle Transport Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Anterograde Axonal Protein Transport Retrograde Neuronal Dense Core Vesicle Transport
Pathways		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins	MHC class II antigen presentation Insulin processing RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases			Hereditary spastic paraplegia (SPG)
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971)	Amyotrophic lateral sclerosis ( 29566793) Rheumatoid arthritis ( 24449572 18794853) Smoking initiation (ever regular vs never regular) ( 30679032)
Interacting Genes		37 interacting genes: ABI3 BBS5 BICDL2 CBY2 CCNH CENPP CEP57L1 CROCC DTX2 GEM IHO1 IMP3 KDM1A KIF5A KIF5B KIF5C KRT13 KRT15 MBIP NDC80 NECAB2 NEFL PDE4DIP QARS1 SMARCB1 SNAP47 STX11 TCF4 TSNAX USHBP1 VPS52 WAC YWHAG YWHAH YWHAQ ZNF417 ZNF572	16 interacting genes: DTNB ITSN1 KCNE3 KIF5B KIF5C KLC3 MAP4K4 NCOA2 NDEL1 PIN1 RAPGEF2 SMN1 TK1 TP53BP2 TSG101 YAP1
Entrez ID		147700	3798
HPRD ID		03212	09108
Ensembl ID		ENSG00000104892	ENSG00000155980
Uniprot IDs		A0A024R0V3 Q6P597	Q12840
PDB IDs			4UXT 4UXY 4UY0
Enriched GO Terms of Interacting Partners?
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