DTX2 and ALKBH4

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		DTX2	ALKBH4
Description		deltex E3 ubiquitin ligase 2	alkB homolog 4, lysine demethylase
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Nuclear Membrane	Nucleolus Cytoplasm Midbody Contractile Ring
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Actin Binding Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, 2-oxoglutarate As One Donor, And Incorporation Of One Atom Each Of Oxygen Into Both Donors Demethylase Activity Oxidative DNA Demethylase Activity Metal Ion Binding
	Biological Process	Notch Signaling Pathway Protein Ubiquitination	Chromatin Organization Protein Demethylation Actomyosin Structure Organization Oxidative DNA Demethylation Cleavage Furrow Ingression Oxidative Demethylation DNA Demethylation Regulation Of Chromatin Organization
Pathways		Activated NOTCH1 Transmits Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus
Drugs
Diseases
GWAS			Morning person ( 30696823)
Interacting Genes		44 interacting genes: ABHD16A ALKBH4 ARNT2 C1orf94 COQ8A DTX1 DTX3 EIF4ENIF1 FAM168A FHL2 GLYCTK GOLGA2 HDC HPCAL1 HPCAL4 KLC3 KRTAP26-1 MDC1 NCALD NCS1 NOTCH1 PLEKHF2 PLSCR1 QARS1 RBPMS RFX6 RHOXF2 RIMBP3 RUNX1 SEC22A SEC23B SPAG8 SPG21 STX12 SUMO1 TRIM54 TRIP13 TRIP6 UBE2D1 UBE2D3 UBE2D4 UBQLN4 VSNL1 ZNF641	12 interacting genes: DTX2 EIF3C EP300 HSF4 MEPCE MLLT1 MLLT3 MTMR6 PSMA6 TES TRAF4 ZFHX3
Entrez ID		113878	54784
HPRD ID		16841	07875
Ensembl ID		ENSG00000091073	ENSG00000160993
Uniprot IDs		Q86UW9	Q9NXW9
PDB IDs		6IR0
Enriched GO Terms of Interacting Partners?
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