CHRNB4 and CHRNA5

  • Number of citations of the paper that reports this interaction (PubMedID 9655874)
  • 74
  • Data Source:
  • HPRD (in vitro)

CHRNB4

CHRNA5

Description cholinergic receptor nicotinic beta 4 subunit cholinergic receptor nicotinic alpha 5 subunit
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Attention function in attention deficit hyperactive disorder ( 26174813)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • BMI (smoking interaction) ( 28443625)
  • BMI in smokers ( 28443625)
  • Body mass index (joint analysis main effects and smoking interaction) ( 28443625)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Diffusing capacity of carbon monoxide ( 30694715)
  • Exhaled carbon monoxide levels ( 25072098)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer ( 28604730 18385738 18780872)
  • Lung cancer in ever smokers ( 28604730)
  • Nicotine dependence ( 18385739 26440539)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
  • Schizophrenia ( 25056061 29483656)
  • Small cell lung carcinoma ( 28604730)
  • Smoking status (heavy vs light) ( 28520984)
  • Squamous cell lung carcinoma ( 28604730)
  • Sudden cardiac arrest ( 21658281)
Interacting Genes 6 interacting genes: CHRNA2 CHRNA3 CHRNA4 CHRNA5 LARP7 UBQLN1 1 interacting genes: CHRNB4
Entrez ID 1143 1138
HPRD ID 00337 00334
Ensembl ID ENSG00000117971 ENSG00000169684
Uniprot IDs P30926 H0YM98 P30532 Q6EWN4
PDB IDs 2ASG 6PV7 6PV8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?