PHB2 and TEAD3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		PHB2	TEAD3
Description		prohibitin 2	TEA domain transcription factor 3
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Cell Surface Postsynaptic Density Nuclear Matrix Axon Protein-containing Complex Presynaptic Active Zone Cell Periphery Glutamatergic Synapse GABA-ergic Synapse	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex
	Molecular Function	Protein Binding Protein C-terminus Binding Estrogen Receptor Binding Amide Binding Sphingolipid Binding Protein N-terminus Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding
	Biological Process	Protein Import Into Nucleus Mitochondrial Calcium Ion Transmembrane Transport Mitochondrion Organization Sister Chromatid Cohesion Response To Wounding Regulation Of Complement Activation Positive Regulation Of Exit From Mitosis Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Apoptotic Process Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Protein Stabilization Positive Regulation Of DNA-binding Transcription Factor Activity Mammary Gland Branching Involved In Thelarche Mammary Gland Alveolus Development Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Retinoic Acid Cellular Response To Hypoxia Positive Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Cytochrome-c Oxidase Activity	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Female Pregnancy Hippo Signaling Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Asymmetric Neuroblast Division
Pathways		Processing of SMDT1	YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription
Drugs		Capsaicin
Diseases
GWAS		Glycated hemoglobin levels ( 28898252) Red blood cell fatty acid levels ( 25500335)	Birth weight ( 31043758) Colorectal cancer or advanced adenoma ( 30510241) Offspring birth weight ( 31043758)
Interacting Genes		19 interacting genes: AFP AKT1 ESR1 EZH2 FHL2 HDAC1 HDAC2 HDAC3 HDAC5 MEF2A MYOD1 NR2F1 NR2F2 PPARG PRKCA PTMA RNF2 TEAD3 UPF2	13 interacting genes: AP4S1 CTBP2 E2F1 E2F3 KIFC2 MYH7 PHB2 PIDD1 SUMO2 VGLL1 VGLL2 WWTR1 YAP1
Entrez ID		11331	7005
HPRD ID		17843	04411
Ensembl ID		ENSG00000215021	ENSG00000007866
Uniprot IDs		Q99623	Q99594
PDB IDs		6IQE	5EMW
Enriched GO Terms of Interacting Partners?
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