PHB2 and MYOD1

Number of citations of the paper that reports this interaction (PubMedID 15173318)
30

Data Source:
HPRD (in vivo)

		PHB2	MYOD1
Description		prohibitin 2	myogenic differentiation 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Cell Surface Postsynaptic Density Nuclear Matrix Axon Protein-containing Complex Presynaptic Active Zone Cell Periphery Glutamatergic Synapse GABA-ergic Synapse	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Myofibril
	Molecular Function	Protein Binding Protein C-terminus Binding Estrogen Receptor Binding Amide Binding Sphingolipid Binding Protein N-terminus Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Transcription Coactivator Activity Protein Binding Chromatin DNA Binding Ubiquitin Protein Ligase Binding Nuclear Hormone Receptor Binding Protein Dimerization Activity E-box Binding Promoter-specific Chromatin Binding
	Biological Process	Protein Import Into Nucleus Mitochondrial Calcium Ion Transmembrane Transport Mitochondrion Organization Sister Chromatid Cohesion Response To Wounding Regulation Of Complement Activation Positive Regulation Of Exit From Mitosis Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Apoptotic Process Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Protein Stabilization Positive Regulation Of DNA-binding Transcription Factor Activity Mammary Gland Branching Involved In Thelarche Mammary Gland Alveolus Development Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Retinoic Acid Cellular Response To Hypoxia Positive Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Cytochrome-c Oxidase Activity	Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II Protein Phosphorylation Muscle Organ Development Myoblast Fate Determination Skeletal Muscle Tissue Development Myoblast Fusion Cellular Response To Starvation Myotube Cell Development Myotube Differentiation Involved In Skeletal Muscle Regeneration Skeletal Muscle Cell Differentiation Muscle Cell Fate Commitment Positive Regulation Of Skeletal Muscle Tissue Regeneration Regulation Of RNA Splicing Skeletal Muscle Fiber Adaptation Histone H3 Acetylation Histone H4 Acetylation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Muscle Cell Differentiation Cellular Response To Tumor Necrosis Factor Cellular Response To Glucocorticoid Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Oxygen Levels Positive Regulation Of Myoblast Fusion Positive Regulation Of SnRNA Transcription By RNA Polymerase II Negative Regulation Of Myoblast Proliferation
Pathways		Processing of SMDT1	Myogenesis Myogenesis
Drugs		Capsaicin
Diseases
GWAS		Glycated hemoglobin levels ( 28898252) Red blood cell fatty acid levels ( 25500335)	Body mass index ( 26426971) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		19 interacting genes: AFP AKT1 ESR1 EZH2 FHL2 HDAC1 HDAC2 HDAC3 HDAC5 MEF2A MYOD1 NR2F1 NR2F2 PPARG PRKCA PTMA RNF2 TEAD3 UPF2	61 interacting genes: ASCL3 BHLHA15 BHLHE40 BHLHE41 C2orf88 CALM1 CALM2 CALM3 CARM1 CDC34 CDK2 CDK4 CDKN1C CIB2 CREBBP CSRP3 ELSPBP1 EP300 FBXO32 HAND1 HDAC1 HEY1 HSP90AA1 ID1 ID2 ID3 ID4 IFRD1 JUN KAT2B KAT5 KPNA3 MDFI MEF2A MEF2C MOS MYOCD NCOR1 NCOR2 NR2F2 PHB2 POLR2G PRKCA PRMT5 PSMD4 PSME2 RB1 RORA RUNX1 RXRA SETD3 SMAD3 SMAD4 SMAD7 SP1 SRF STAT3 SUV39H1 TCF3 TCF4 TWIST1
Entrez ID		11331	4654
HPRD ID		17843	01166
Ensembl ID		ENSG00000215021	ENSG00000129152
Uniprot IDs		Q99623	P15172
PDB IDs		6IQE
Enriched GO Terms of Interacting Partners?
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