LYST and HNRNPM

Number of citations of the paper that reports this interaction (PubMedID 11984006)
32

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vivo)

		LYST	HNRNPM
Description		lysosomal trafficking regulator	heterogeneous nuclear ribonucleoprotein M
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Cytoskeleton	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Membrane Nuclear Matrix Paraspeckles Collagen-containing Extracellular Matrix Extracellular Exosome Catalytic Step 2 Spliceosome Post-mRNA Release Spliceosomal Complex Ribonucleoprotein Complex
	Molecular Function	Protein Binding	RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding
	Biological Process	Lysosome Organization Protein Transport Leukocyte Chemotaxis Melanosome Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Mast Cell Secretory Granule Organization Natural Killer Cell Mediated Cytotoxicity Defense Response To Bacterium Defense Response To Protozoan Pigmentation Defense Response To Virus	Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Regulation Of MRNA Stability Involved In Response To Oxidative Stress
Pathways			FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases		Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS		Post bronchodilator FEV1/FVC ratio ( 26634245) Systemic lupus erythematosus ( 26502338 19838195)	Coronary artery disease ( 29212778)
Interacting Genes		24 interacting genes: ATN1 CALM1 CELF4 CENPJ CNTROB CSNK2B DNAJC14 EFS ESRRA ESS2 HGS HNRNPM KPNB1 MED12 MRPL17 MRPS31 NCDN PCBP4 TNNI3 VTA1 YWHAB YWHAQ YWHAZ ZNF521	25 interacting genes: AKAP9 APC CDC5L CEACAM5 ECPAS GMCL2 HNRNPF JUN LMO2 LMO3 LYST PLRG1 PRRC2A RBM4 RBM4B SMARCB1 STAT3 TCERG1 TEKT4 U2AF1 UBC UBE2I WDR77 YWHAG ZNF207
Entrez ID		1130	4670
HPRD ID		06060	01188
Ensembl ID		ENSG00000143669	ENSG00000099783
Uniprot IDs		Q99698	P52272 Q59ES8
PDB IDs			2DGV 2DH9 2DO0 2OT8
Enriched GO Terms of Interacting Partners?
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