DDX20 and SNRPD3

Number of citations of the paper that reports this interaction (PubMedID 10601333)
85

Data Source:
HPRD (in vivo, in vitro)

		DDX20	SNRPD3
Description		DEAD-box helicase 20	small nuclear ribonucleoprotein D3 polypeptide
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Membrane SMN Complex SMN-Sm Protein Complex RNA Polymerase II Transcription Repressor Complex Gemini Of Coiled Bodies	Commitment Complex Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U7 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Telomerase Holoenzyme Complex Cytosol Nuclear Body Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex
	Molecular Function	DNA Binding RNA Binding RNA Helicase Activity Protein Binding ATP Binding Protein Domain Specific Binding Protein Binding, Bridging Histone Deacetylase Binding Repressing Transcription Factor Binding	RNA Binding Protein Binding Enzyme Binding Telomerase RNA Binding Histone Pre-mRNA DCP Binding U7 SnRNA Binding U1 SnRNP Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly RNA Processing Negative Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process Oogenesis Regulation Of Steroid Biosynthetic Process Import Into Nucleus	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription Protein Methylation Histone MRNA Metabolic Process RNA Splicing Import Into Nucleus
Pathways		snRNP Assembly	SLBP independent Processing of Histone Pre-mRNAs snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Drugs
Diseases
GWAS		Body mass index ( 29273807) Metabolite levels ( 23823483)	Acne (severe) ( 24927181)
Interacting Genes		33 interacting genes: AGO2 APP CRYAB DHX9 ETV3 GEMIN2 GEMIN4 GEMIN5 HDAC2 HDAC5 LSM2 NCOR1 NCOR2 NR0B2 NUFIP1 PRRC2A RN7SL1 RNU1-1 RNU2-1 SIN3A SMN1 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNUPN STXBP2 STXBP3 TP53	26 interacting genes: CASP8 CLNS1A CRY1 DDX20 GEMIN2 GEMIN5 GEMIN6 GEMIN7 IL12RB1 IL7R LSM3 LSM7 NR1I3 PRMT5 RBL1 SMN1 SMN2 SNRPB SNRPE SNRPG SREK1 STRAP STXBP2 STXBP3 TRDMT1 WDR77
Entrez ID		11218	6634
HPRD ID		05859	03039
Ensembl ID		ENSG00000064703	ENSG00000100028
Uniprot IDs		Q9H4N4 Q9UHI6	P62318
PDB IDs		2OXC 3B7G	1D3B 3CW1 3JCR 3PGW 3VRI 4PJO 4WZJ 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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