SNRPD3 and TRDMT1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		SNRPD3	TRDMT1
Description		small nuclear ribonucleoprotein D3 polypeptide	tRNA aspartic acid methyltransferase 1
Image
GO Annotations	Cellular Component	Commitment Complex Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U7 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Telomerase Holoenzyme Complex Cytosol Nuclear Body Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex	Nucleoplasm Cytoplasm
	Molecular Function	RNA Binding Protein Binding Enzyme Binding Telomerase RNA Binding Histone Pre-mRNA DCP Binding U7 SnRNA Binding U1 SnRNP Binding	RNA Binding TRNA Methyltransferase Activity TRNA (cytosine-5-)-methyltransferase Activity
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription Protein Methylation Histone MRNA Metabolic Process RNA Splicing Import Into Nucleus	Response To Amphetamine TRNA Modification TRNA Methylation TRNA Stabilization
Pathways		SLBP independent Processing of Histone Pre-mRNAs snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	tRNA modification in the nucleus and cytosol
Drugs			Pentamidine S-adenosyl-L-homocysteine Glycerin
Diseases
GWAS		Acne (severe) ( 24927181)	Telomere length ( 24478790)
Interacting Genes		26 interacting genes: CASP8 CLNS1A CRY1 DDX20 GEMIN2 GEMIN5 GEMIN6 GEMIN7 IL12RB1 IL7R LSM3 LSM7 NR1I3 PRMT5 RBL1 SMN1 SMN2 SNRPB SNRPE SNRPG SREK1 STRAP STXBP2 STXBP3 TRDMT1 WDR77	14 interacting genes: APP COPS6 DDX24 EEF1A1 GBE1 LRIF1 NFRKB RBM48 SETDB1 SNRPD3 STX1A TBC1D2B UNC119 UTP14A
Entrez ID		6634	1787
HPRD ID		03039	16001
Ensembl ID		ENSG00000100028	ENSG00000107614
Uniprot IDs		P62318	A0A0U1U562 B4DQZ2 O14717 Q6ICS7 Q7Z3E4
PDB IDs		1D3B 3CW1 3JCR 3PGW 3VRI 4PJO 4WZJ 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9	1G55
Enriched GO Terms of Interacting Partners?
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