TMED2 and SEC23B

Number of citations of the paper that reports this interaction (PubMedID 9472029)
98

Data Source:
BioGRID (unspecified method)

		TMED2	SEC23B
Description		transmembrane p24 trafficking protein 2	SEC23 homolog B, COPII coat complex component
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle COPI-coated Vesicle COPI-coated Vesicle Membrane Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Zymogen Granule Membrane Intracellular Membrane-bounded Organelle	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endomembrane System COPII Vesicle Coat Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding	GTPase Activator Activity Protein Binding Zinc Ion Binding
	Biological Process	Neural Tube Closure Maternal Placenta Development Heart Looping Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Golgi Organization Positive Regulation Of Gene Expression Somite Rostral/caudal Axis Specification Negative Regulation Of GTPase Activity Multicellular Organism Growth Cargo Loading Into Vesicle Post-anal Tail Morphogenesis COPI Coating Of Golgi Vesicle COPII Vesicle Coating Labyrinthine Layer Blood Vessel Development Protein Localization To Plasma Membrane	Intracellular Protein Transport Positive Regulation Of GTPase Activity Cargo Loading Into COPII-coated Vesicle
Pathways		Pre-NOTCH Processing in Golgi COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases			Congenital dyserythropoietic anemias (CDAs)
GWAS		Educational attainment ( 25201988) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		9 interacting genes: AKT2 ARF1 ARFGAP1 COPA GOLGA2 GORASP1 GORASP2 SEC23B TMED10	21 interacting genes: CPSF7 DTX2 FATE1 FBXW5 GALNT1 HOXA3 KDELR1 MAN2A1 NINL PRRC1 SEC24C SEC24D SKP1 SRPK1 SRPK2 SYNE4 TMED1 TMED10 TMED2 TMED9 UGT1A1
Entrez ID		10959	10483
HPRD ID		17984	11543
Ensembl ID		ENSG00000086598	ENSG00000101310
Uniprot IDs		Q15363 Q6FHT8	A0A2R8YFH5 Q15437
PDB IDs		5AZW
Enriched GO Terms of Interacting Partners?
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