SEC23B and NINL

		SEC23B	NINL
Description		SEC23 homolog B, COPII coat complex component	ninein like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endomembrane System COPII Vesicle Coat Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site	Centrosome Cytosol Microtubule Intercellular Bridge
	Molecular Function	GTPase Activator Activity Protein Binding Zinc Ion Binding	Calcium Ion Binding Protein Binding
	Biological Process	Intracellular Protein Transport Positive Regulation Of GTPase Activity Cargo Loading Into COPII-coated Vesicle	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Microtubule Anchoring At Centrosome Ciliary Basal Body-plasma Membrane Docking
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases		Congenital dyserythropoietic anemias (CDAs)
GWAS			Macular thickness ( 30535121) Telomere length ( 30185882) Urate levels ( 31578528)
Interacting Genes		21 interacting genes: CPSF7 DTX2 FATE1 FBXW5 GALNT1 HOXA3 KDELR1 MAN2A1 NINL PRRC1 SEC24C SEC24D SKP1 SRPK1 SRPK2 SYNE4 TMED1 TMED10 TMED2 TMED9 UGT1A1	50 interacting genes: AKAP17A APEX2 APMAP AURKB CBY2 CCDC130 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 ELOA EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 KRT1 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 POLR3F RBM41 RCOR3 RGS2 RIBC2 SEC23B SH2D4A SH3BP5L SYT17 TCEANC TNNT1 TSPYL4 UTP14A ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646
Entrez ID		10483	22981
HPRD ID		11543	11120
Ensembl ID		ENSG00000101310	ENSG00000101004
Uniprot IDs		A0A2R8YFH5 Q15437	Q9Y2I6
PDB IDs
Enriched GO Terms of Interacting Partners?
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