TFG and SPG21

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TFG	SPG21
Description		trafficking from ER to golgi regulator	SPG21 abhydrolase domain containing, maspardin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Endoplasmic Reticulum Exit Site	Golgi Apparatus Cytosol Endosome Membrane Trans-Golgi Network Transport Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding CD4 Receptor Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling COPII Vesicle Coating	Antigen Receptor-mediated Signaling Pathway
Pathways		COPII-mediated vesicle transport
Drugs
Diseases		Non-small cell lung cancer Thyroid cancer	Hereditary spastic paraplegia (SPG)
GWAS
Interacting Genes		32 interacting genes: ANXA11 ARHGEF16 ARL15 BOLL CEP126 CEP55 CRMP1 CSTF2 ERG28 EWSR1 GBP2 GPRASP1 GRB2 HGS HNRNPF MAGED1 MAPK1IP1L MED21 MYOT PEF1 PIN1 PLSCR1 PTPN6 RBPMS RIPPLY2 SEC24A SPG21 STAT5B TOMM70 TRIM25 TSSK2 VPS37C	37 interacting genes: AGTRAP AKIRIN2 ARL6IP1 CCDC102B CCDC33 CD4 CMTM5 CRYAA CTPS2 CUTC DTX2 DTX3L EFHC2 FAM114A1 GGA2 GSK3A IKZF3 INCA1 KRT15 LMNA MID2 MTMR9 PRPS1 RABAC1 REEP6 RTN4 S100B SPRED2 TCF12 TCF4 TFG TRAF1 TRAF2 TRIM23 TRIM54 TRIM9 ZNF263
Entrez ID		10342	51324
HPRD ID		03932	10492
Ensembl ID		ENSG00000114354	ENSG00000090487
Uniprot IDs		Q05BK6 Q92734	A0A024R5Y1 Q9NZD8
PDB IDs
Enriched GO Terms of Interacting Partners?
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