SPG21 and FAM114A1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		SPG21	FAM114A1
Description		SPG21 abhydrolase domain containing, maspardin	family with sequence similarity 114 member A1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol Endosome Membrane Trans-Golgi Network Transport Vesicle Intracellular Membrane-bounded Organelle	Nucleoplasm Golgi Apparatus Cytosol
	Molecular Function	Protein Binding CD4 Receptor Binding	Protein Binding
	Biological Process	Antigen Receptor-mediated Signaling Pathway
Pathways
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS			Alcohol dependence ( 24166409) Allergic disease (asthma, hay fever or eczema) ( 29785011) Allergic sensitization ( 23817571) Asthma or allergic disease (pleiotropy) ( 29785011) Helicobacter pylori serologic status ( 23652523) Mean corpuscular volume ( 27863252) Moderate or severe diarrhoea in darapladib-treated cardiovascular disease (time to event) ( 28753643)
Interacting Genes		37 interacting genes: AGTRAP AKIRIN2 ARL6IP1 CCDC102B CCDC33 CD4 CMTM5 CRYAA CTPS2 CUTC DTX2 DTX3L EFHC2 FAM114A1 GGA2 GSK3A IKZF3 INCA1 KRT15 LMNA MID2 MTMR9 PRPS1 RABAC1 REEP6 RTN4 S100B SPRED2 TCF12 TCF4 TFG TRAF1 TRAF2 TRIM23 TRIM54 TRIM9 ZNF263	6 interacting genes: AGTRAP CMTM5 RAB2A RAB2B SPG21 TNS2
Entrez ID		51324	92689
HPRD ID		10492	11282
Ensembl ID		ENSG00000090487	ENSG00000197712
Uniprot IDs		A0A024R5Y1 Q9NZD8	A1MMZ0 Q8IWE2
PDB IDs
Enriched GO Terms of Interacting Partners?
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