HDAC5 and MEF2C

  • Number of citations of the paper that reports this interaction (PubMedID 10737771)
  • 177
  • Data Source:
  • HPRD (in vitro)

HDAC5

MEF2C

Description histone deacetylase 5 myocyte enhancer factor 2C
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Accelerometer-based physical activity measurement (average acceleration) ( 29899525)
  • Alcohol consumption ( 31358974)
  • Alcohol consumption (drinks per week) ( 30643258)
  • Alzheimer's disease ( 31473137)
  • Alzheimer's disease (late onset) ( 24162737)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Attention deficit hyperactivity disorder ( 29325848)
  • Bipolar disorder lithium response (categorical) or schizophrenia ( 29121268)
  • Body mass index ( 26426971)
  • Bone mineral density ( 21533022 24249740 23572186)
  • Bone mineral density (hip) ( 19801982)
  • Bone mineral density (total hip) ( 29883787)
  • Bone mineral density (Ward's triangle area) ( 27397699)
  • Chronotype ( 30696823)
  • Cognitive ability ( 29186694)
  • Cognitive ability (MTAG) ( 29186694)
  • Depression ( 29700475)
  • Femoral neck bone mineral density ( 29499414 22504420)
  • General cognitive ability ( 29844566)
  • Glomerular filtration rate in chronic kidney disease ( 26420894)
  • Height ( 20881960 25282103 25429064)
  • Household income (MTAG) ( 31844048)
  • Intelligence ( 28530673)
  • Intelligence (MTAG) ( 29326435)
  • Major depressive disorder ( 27479909)
  • Mean corpuscular hemoglobin ( 27863252)
  • Mean corpuscular volume ( 27863252)
  • Mean platelet volume ( 22139419 27863252)
  • Morning person ( 30696823)
  • Multiple sclerosis ( 31604244)
  • Number of sexual partners ( 30643258)
  • Photic sneeze reflex ( 27182965)
  • Platelet count ( 22139419 27863252)
  • Platelet distribution width ( 27863252)
  • Plateletcrit ( 27863252)
  • Red blood cell count ( 27863252)
  • Regular attendance at a religious group ( 29970889)
  • Retinal arteriolar caliber ( 23776548)
  • Retinal vascular caliber ( 21060863)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 25056061 30285260)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Tonometry ( 17903302)
  • Vascular endothelial growth factor levels ( 26910538)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for body mass index ( 28448500)
Interacting Genes 60 interacting genes: ANKRA2 ANKRD11 ATF3 BCL6 BCOR BRMS1 CAMK1 CAMTA2 CBX5 CIITA CTBP1 DDX20 DYRK1B EEF1G ESR1 GABARAP GATA1 GATA2 GCM1 GNB1 H3C1 HDAC3 HDAC7 HIF1A HOXC11 HR JDP2 KLF4 MAFF MEF2A MEF2C MEF2D NCOR1 NCOR2 NFATC1 NFKB2 NFKBIE NRIP1 PHB2 PKN1 PKN2 PRKAA1 PRKCD PRKD1 RFXANK RUNX3 SFN SIK1 SIK2 SIK3 SLC2A4RG SMAD3 SUV39H1 TAB2 UBC UBE2I YWHAB YWHAE YWHAQ ZBTB16 30 interacting genes: ASCL1 CCNB1 CDK1 COPS5 CSNK2A1 EP300 EPAS1 GATA4 HDAC4 HDAC5 HDAC7 HDAC9 MAPK14 MAPK7 MEF2D MYOD1 MYOG NCOA2 NOTCH1 PLA2G12A SMAD2 SOX18 SP1 SPTBN1 TEAD1 TWIST2 UBE2I VGLL2 VGLL4 YWHAZ
Entrez ID 10014 4208
HPRD ID 09246 02809
Ensembl ID ENSG00000108840 ENSG00000081189
Uniprot IDs Q9UQL6 A0A024RAL6 A0A024RAL7 A0A0D9SGI5 D8L7E9 Q06413
PDB IDs 5UWI
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?