TUBA4A - Wiki-MPM

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
ENO2	enolase 2	Glycolysis Gluconeogenesis	2-Phosphoglycolic Acid
GRM7	glutamate metabotropic receptor 7	G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors)	Glutamic acid
MAGED1	MAGE family member D1	NRAGE signals death through JNK Caspase activation via Dependence Receptors in the absence of ligand
ZAP70	zeta chain of T cell receptor associated protein kinase 70	Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules	Staurosporine Fostamatinib	Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency
ARHGAP1	Rho GTPase activating protein 1	Rho GTPase cycle
EPB41	erythrocyte membrane protein band 4.1	Neurexins and neuroligins		Hereditary elliptocytosis (HE)
GPHN	gephyrin	Molybdenum cofactor biosynthesis	Formic acid Imidazole Propanoic acid	Hyperekplexia
MAPT	microtubule associated protein tau	Caspase-mediated cleavage of cytoskeletal proteins	Lansoprazole Astemizole Paclitaxel Docetaxel Flortaucipir F-18	Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease Frontotemporal lobar degeneration (FTLD), including: Pick disease of brain; Frontotemporal dementia (FTD); Ubiquitin-positive frontotemporal dementia (UP-FTD); Progressive supranuclear palsy type 1 (PSNP1); Inclusion body myopathy with early-onset paget disease and frontotemporal dementia (IBMPFD); Frontotemporal dementia, chromosome 3-linked (FTD3) Progressive supranuclear palsy (PSP); Steele-Richardson-Olszewski syndrome
MARK4	microtubule affinity regulating kinase 4	Anchoring of the basal body to the plasma membrane	Fostamatinib
NCALD	neurocalcin delta	Activation of Ca-permeable Kainate Receptor
PFDN4	prefoldin subunit 4	Prefoldin mediated transfer of substrate to CCT/TriC
RTN4	reticulon 4	Axonal growth inhibition (RHOA activation)
SIRT2	sirtuin 2	Initiation of Nuclear Envelope (NE) Reformation	Cambinol
STARD13	StAR related lipid transfer domain containing 13	Rho GTPase cycle
TBCB	tubulin folding cofactor B	Post-chaperonin tubulin folding pathway
TBCE	tubulin folding cofactor E	Post-chaperonin tubulin folding pathway		Hypoparathyroidism-retardation-dysmorphism syndrome; Sanjad-Sakati syndrome Kenny-Caffey syndrome
C4orf17	chromosome 4 open reading frame 17
CALB2	calbindin 2		Calcium citrate Calcium Phosphate Calcium levulinate Calcium phosphate dihydrate
LGALS2	galectin 2		Beta-D-Glucose
MAP1A	microtubule associated protein 1A		Estramustine

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