Search Results for: TSC1

110 interactions involving TSC1 - TSC complex subunit 1 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
SH2D2A SH2 domain containing 2A
  • VEGFA-VEGFR2 Pathway
SHC3 SHC adaptor protein 3
  • Signalling to RAS
  • Signalling to RAS
  • RAF/MAP kinase cascade
  • RET signaling
SMG9 SMG9 nonsense mediated mRNA decay factor
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
SOX4 SRY-box transcription factor 4
  • Deactivation of the beta-catenin transactivating complex
SPAG8 sperm associated antigen 8
SUOX sulfite oxidase
  • Sulfide oxidation to sulfate
  • {[2-Amino-4-oxo-6,7-di(sulfanyl-κS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum
TBC1D7 TBC1 domain family member 7
  • TBC/RABGAPs
TBX6 T-box transcription factor 6
TCF7L2 transcription factor 7 like 2
  • Formation of the beta-catenin:TCF transactivating complex
  • Formation of the beta-catenin:TCF transactivating complex
  • Deactivation of the beta-catenin transactivating complex
  • Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
  • Ca2+ pathway
  • Binding of TCF/LEF:CTNNB1 to target gene promoters
  • Repression of WNT target genes
  • Repression of WNT target genes
  • Signaling by TCF7L2 mutants
  • Transcriptional Regulation by VENTX
  • RUNX3 regulates WNT signaling
  • Type II diabetes mellitus
TFAP2D transcription factor AP-2 delta
  • Negative regulation of activity of TFAP2 (AP-2) family transcription factors
  • Negative regulation of activity of TFAP2 (AP-2) family transcription factors
  • Activation of the TFAP2 (AP-2) family of transcription factors
TLE5 TLE family member 5, transcriptional modulator
  • Repression of WNT target genes
TNS2 tensin 2
TSC2 TSC complex subunit 2
  • Macroautophagy
  • Inhibition of TSC complex formation by PKB
  • AKT phosphorylates targets in the cytosol
  • Energy dependent regulation of mTOR by LKB1-AMPK
  • TP53 Regulates Metabolic Genes
  • Constitutive Signaling by AKT1 E17K in Cancer
  • TBC/RABGAPs
  • Lymphangioleiomyomatosis (LAM)
  • Tuberous sclerosis complex (TSC); Bourneville-Pringle disease
TSGA10IP testis specific 10 interacting protein
TSHZ3 teashirt zinc finger homeobox 3
VENTX VENT homeobox
  • Senescence-Associated Secretory Phenotype (SASP)
  • Transcriptional Regulation by VENTX
VEZF1 vascular endothelial zinc finger 1
VGLL3 vestigial like family member 3
VPS37C VPS37C subunit of ESCRT-I
  • Budding and maturation of HIV virion
  • Membrane binding and targetting of GAG proteins
  • Endosomal Sorting Complex Required For Transport (ESCRT)
  • HCMV Late Events
  • Late endosomal microautophagy
YPEL3 yippee like 3

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