Search Results for: TSC1

110 interactions involving TSC1 - TSC complex subunit 1 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
  • Activation of BAD and translocation to mitochondria
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • RHO GTPases activate PKNs
  • TP53 Regulates Metabolic Genes
  • Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
  • Phenethyl Isothiocyanate
AQP1 aquaporin 1 (Colton blood group)
  • Erythrocytes take up carbon dioxide and release oxygen
  • Erythrocytes take up oxygen and release carbon dioxide
  • Vasopressin regulates renal water homeostasis via Aquaporins
  • Passive transport by Aquaporins
  • Acetazolamide
  • B-nonylglucoside
  • Mersalyl
BECN1 beclin 1
  • Macroautophagy
  • Ub-specific processing proteases
  • Translation of Replicase and Assembly of the Replication Transcription Complex
  • Translation of Replicase and Assembly of the Replication Transcription Complex
  • Estradiol
  • Estradiol acetate
  • Estradiol benzoate
  • Estradiol cypionate
  • Estradiol dienanthate
  • Estradiol valerate
SHC3 SHC adaptor protein 3
  • Signalling to RAS
  • Signalling to RAS
  • RAF/MAP kinase cascade
  • RET signaling
CCND2 cyclin D2
  • Cyclin D associated events in G1
  • Regulation of RUNX1 Expression and Activity
  • Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
  • Testicular cancer
EZR ezrin
  • Netrin-1 signaling
  • Recycling pathway of L1
  • Recycling pathway of L1
MSN moesin
  • Recycling pathway of L1
  • Recycling pathway of L1
  • Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
MYLIP myosin regulatory light chain interacting protein
  • VLDLR internalisation and degradation
  • NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake
  • Antigen processing: Ubiquitination & Proteasome degradation
TFAP2D transcription factor AP-2 delta
  • Negative regulation of activity of TFAP2 (AP-2) family transcription factors
  • Negative regulation of activity of TFAP2 (AP-2) family transcription factors
  • Activation of the TFAP2 (AP-2) family of transcription factors
CCL28 C-C motif chemokine ligand 28
  • Chemokine receptors bind chemokines
  • G alpha (i) signalling events
FOXH1 forkhead box H1
  • Signaling by NODAL
  • Signaling by Activin
NF2 neurofibromin 2
  • Regulation of actin dynamics for phagocytic cup formation
  • RHO GTPases activate PAKs
  • Malignant pleural mesothelioma
  • Noonan syndrome and related disorders, including: Noonan syndrome (NS); Leopard syndrome (LS); Noonan syndrome-like with loose anagen hair (NS/LAH); CBL-mutation associated syndrome (CBL); Neurofibromatosis type 1 (NF1); Neurofibromatosis type 2 (NF2); Neurofibromatosis-Noonan syndrome (NFNS); Legius syndrome; Cardiofaciocutaneous syndrome (CFCS); Costello syndrome (CS)
PATL1 PAT1 homolog 1, processing body mRNA decay factor
  • mRNA decay by 5' to 3' exoribonuclease
  • mRNA decay by 5' to 3' exoribonuclease
PLK2 polo like kinase 2
  • TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
  • CD163 mediating an anti-inflammatory response
  • Fostamatinib
PRMT6 protein arginine methyltransferase 6
  • RMTs methylate histone arginines
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RDX radixin
  • Recycling pathway of L1
  • Recycling pathway of L1
  • 1D-myo-inositol 1,4,5-trisphosphate
VENTX VENT homeobox
  • Senescence-Associated Secretory Phenotype (SASP)
  • Transcriptional Regulation by VENTX
BAG3 BAG cochaperone 3
  • Regulation of HSF1-mediated heat shock response
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2
  • Mitochondrial protein import
DOK5 docking protein 5
  • RET signaling

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