Search Results for: TERT

89 interactions involving TERT - telomerase reverse transcriptase found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
ACAA2 acetyl-CoA acyltransferase 2
  • Mitochondrial Fatty Acid Beta-Oxidation
DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2
  • Regulation of TP53 Activity through Phosphorylation
FAAP24 FA core complex associated protein 24
  • Fanconi Anemia Pathway
HSPA4 heat shock protein family A (Hsp70) member 4
  • Regulation of HSF1-mediated heat shock response
  • Phenethyl Isothiocyanate
IREB2 iron responsive element binding protein 2
  • Iron uptake and transport
MAP2K5 mitogen-activated protein kinase kinase 5
  • Signalling to ERK5
  • Fostamatinib
NCL nucleolin
  • Major pathway of rRNA processing in the nucleolus and cytosol
NSD3 nuclear receptor binding SET domain protein 3
  • PKMTs methylate histone lysines
PFDN1 prefoldin subunit 1
  • Prefoldin mediated transfer of substrate to CCT/TriC
RPS6KB1 ribosomal protein S6 kinase B1
  • mTORC1-mediated signalling
SMG5 SMG5 nonsense mediated mRNA decay factor
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
SMG6 SMG6 nonsense mediated mRNA decay factor
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
  • Grn163l
SOX3 SRY-box transcription factor 3
  • Deactivation of the beta-catenin transactivating complex
  • Septo-optic dysplasia
  • Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
  • 46,XX disorders of sex development (Disorders of gonadal development), including: Ovotesticular DSD; Testicular DSD; Ovarian dysgenesis
  • Syndromic X-linked mental retardation, including: Turner type (MRXST); Siderius type (MRXSSD) ; Cabezas type (MRXC); Raymond type (MRXSR); Type10 (MRXS10); Type14 (MRXS14); Mental retardation with isolated growth hormone deficiency (MRGH)
SOX4 SRY-box transcription factor 4
  • Deactivation of the beta-catenin transactivating complex
TIMM21 translocase of inner mitochondrial membrane 21
  • Mitochondrial protein import
TPP1 tripeptidyl peptidase 1
  • XBP1(S) activates chaperone genes
  • Neuronal ceroid lipofuscinosis, including: Infantile Neuronal Ceroid Lipofuscinosis (INCL)/ Santavuori-Haltia Disease (CLN1); Late-Infantile Neuronal Ceroid Lipofuscinosis (LINCL)/ Jansky-Bielschowsky Disease (CLN2); Juvenile Neuronal Ceroid Lipofuscinosis (JNCL)/Batten Disease/ Spielmeyer-Vogt Disease (CLN3); Adult Neuronal Ceroid Lipofuscinosis (ANCL)/ Kufs Disease (CLN4); LINCL variant (CLN5, CLN6, CLN7, CLN8); Batten Disease variant (CLN9); Congenital NCL (CLN10)
  • Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
U2SURP U2 snRNP associated SURP domain containing
  • mRNA Splicing - Major Pathway
CBLC Cbl proto-oncogene C
CIB1 calcium and integrin binding 1
  • Calcium citrate
  • Calcium Phosphate
  • Calcium phosphate dihydrate
DACH1 dachshund family transcription factor 1

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