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CREG1 |
cellular repressor of E1A stimulated genes 1 |
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CTBP1 |
C-terminal binding protein 1 |
- Deactivation of the beta-catenin transactivating complex
- SUMOylation of transcription cofactors
- Repression of WNT target genes
- Signaling by TCF7L2 mutants
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CTSV |
cathepsin V |
- Endosomal/Vacuolar pathway
- Degradation of the extracellular matrix
- Activation of Matrix Metalloproteinases
- Trafficking and processing of endosomal TLR
- Assembly of collagen fibrils and other multimeric structures
- MHC class II antigen presentation
- RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
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- 3-amino-5-phenylpentane
- 4-Methylpiperazin-1-Yl Carbonyl Group
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CUX1 |
cut like homeobox 1 |
- Signaling by cytosolic FGFR1 fusion mutants
- Signaling by FGFR1 in disease
- Intra-Golgi traffic
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DGKZ |
diacylglycerol kinase zeta |
- Effects of PIP2 hydrolysis
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- alpha-Tocopherol succinate
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DNMT1 |
DNA methyltransferase 1 |
- PRC2 methylates histones and DNA
- NoRC negatively regulates rRNA expression
- SUMOylation of DNA methylation proteins
- DNA methylation
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- Procaine
- Azacitidine
- Procainamide
- Flucytosine
- Decitabine
- Palifosfamide
- Epigallocatechin gallate
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DVL1 |
dishevelled segment polarity protein 1 |
- TCF dependent signaling in response to WNT
- WNT mediated activation of DVL
- PCP/CE pathway
- PCP/CE pathway
- Degradation of DVL
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- Negative regulation of TCF-dependent signaling by DVL-interacting proteins
- RHO GTPases Activate Formins
- WNT5:FZD7-mediated leishmania damping
- WNT5:FZD7-mediated leishmania damping
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DYRK1A |
dual specificity tyrosine phosphorylation regulated kinase 1A |
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- N-(5-{[(2S)-4-amino-2-(3-chlorophenyl)butanoyl]amino}-1H-indazol-3-yl)benzamide
- Fostamatinib
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E2F1 |
E2F transcription factor 1 |
- Activation of NOXA and translocation to mitochondria
- Inhibition of replication initiation of damaged DNA by RB1/E2F1
- Transcription of E2F targets under negative control by DREAM complex
- Transcription of E2F targets under negative control by DREAM complex
- Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
- Activation of PUMA and translocation to mitochondria
- Pre-NOTCH Transcription and Translation
- Pre-NOTCH Transcription and Translation
- Oxidative Stress Induced Senescence
- Oncogene Induced Senescence
- TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
- CDC6 association with the ORC:origin complex
- G2 Phase
- Cyclin E associated events during G1/S transition
- G1/S-Specific Transcription
- G1/S-Specific Transcription
- Cyclin D associated events in G1
- Cyclin A:Cdk2-associated events at S phase entry
- Transcriptional Regulation by E2F6
- Transcriptional regulation of granulopoiesis
- Transcriptional regulation of granulopoiesis
- Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
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E2F2 |
E2F transcription factor 2 |
- Oxidative Stress Induced Senescence
- Oncogene Induced Senescence
- CDC6 association with the ORC:origin complex
- Cyclin D associated events in G1
- Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
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E2F3 |
E2F transcription factor 3 |
- Pre-NOTCH Transcription and Translation
- Pre-NOTCH Transcription and Translation
- Oxidative Stress Induced Senescence
- Oncogene Induced Senescence
- CDC6 association with the ORC:origin complex
- G2 Phase
- Cyclin D associated events in G1
- Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
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E2F4 |
E2F transcription factor 4 |
- Transcription of E2F targets under negative control by DREAM complex
- Transcription of E2F targets under negative control by DREAM complex
- Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
- G0 and Early G1
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
- TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
- Cyclin E associated events during G1/S transition
- G1/S-Specific Transcription
- G1/S-Specific Transcription
- Cyclin D associated events in G1
- Cyclin A:Cdk2-associated events at S phase entry
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E4F1 |
E4F transcription factor 1 |
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EID1 |
EP300 interacting inhibitor of differentiation 1 |
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ELF1 |
E74 like ETS transcription factor 1 |
- RUNX1 regulates transcription of genes involved in BCR signaling
- RUNX1 regulates transcription of genes involved in interleukin signaling
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ENC1 |
ectodermal-neural cortex 1 |
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EP300 |
E1A binding protein p300 |
- Regulation of gene expression by Hypoxia-inducible Factor
- RORA activates gene expression
- Polo-like kinase mediated events
- Pre-NOTCH Transcription and Translation
- Pre-NOTCH Transcription and Translation
- PPARA activates gene expression
- PPARA activates gene expression
- Formation of the beta-catenin:TCF transactivating complex
- Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
- NOTCH1 Intracellular Domain Regulates Transcription
- NOTCH1 Intracellular Domain Regulates Transcription
- NOTCH2 intracellular domain regulates transcription
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
- HATs acetylate histones
- Attenuation phase
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
- SUMOylation of transcription cofactors
- Circadian Clock
- B-WICH complex positively regulates rRNA expression
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- CD209 (DC-SIGN) signaling
- Metalloprotease DUBs
- Formation of TC-NER Pre-Incision Complex
- Transcription-Coupled Nucleotide Excision Repair (TC-NER)
- Dual incision in TC-NER
- Gap-filling DNA repair synthesis and ligation in TC-NER
- TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
- Regulation of TP53 Activity through Acetylation
- Regulation of TP53 Activity through Methylation
- PI5P Regulates TP53 Acetylation
- Activation of the TFAP2 (AP-2) family of transcription factors
- RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
- RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
- RUNX3 regulates NOTCH signaling
- RUNX3 regulates NOTCH signaling
- Regulation of RUNX3 expression and activity
- RUNX3 regulates p14-ARF
- NOTCH3 Intracellular Domain Regulates Transcription
- NOTCH3 Intracellular Domain Regulates Transcription
- NOTCH4 Intracellular Domain Regulates Transcription
- Estrogen-dependent gene expression
- NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
- NGF-stimulated transcription
- NGF-stimulated transcription
- TRAF3-dependent IRF activation pathway
- TRAF6 mediated IRF7 activation
- FOXO-mediated transcription of cell death genes
- Transcriptional regulation of granulopoiesis
- Transcriptional regulation of granulopoiesis
- Regulation of FOXO transcriptional activity by acetylation
- Regulation of FOXO transcriptional activity by acetylation
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- Rubinstein-Taybi syndrome
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FANCC |
FA complementation group C |
- Fanconi Anemia Pathway
- TP53 Regulates Transcription of DNA Repair Genes
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FBP1 |
fructose-bisphosphatase 1 |
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- Adenosine phosphate
- 2,5-Anhydroglucitol-1,6-Biphosphate
- {4-[3-(6,7-Diethoxy-Quinazolin-4-Ylamino)-Phenyl]-Thiazol-2-Yl}-Methanol
- Mdl-29951
- Fructose-6-phosphate
- MB-07803
- Managlinat dialanetil
- N-[7-(3-AMINOPHENYL)-5-METHOXY-1,3-BENZOXAZOL-2-YL]-2,5-DICHLOROBENZENESULFONAMIDE
- 2,5-DICHLORO-N-(5-CHLORO-1,3-BENZOXAZOL-2-YL)BENZENESULFONAMIDE
- 2,5-DICHLORO-N-[5-METHOXY-7-(6-METHOXYPYRIDIN-3-YL)-1,3-BENZOXAZOL-2-YL]BENZENESULFONAMIDE
- 4-AMINO-N-[(2-SULFANYLETHYL)CARBAMOYL]BENZENESULFONAMIDE
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- Fructose-1,6-bisphosphatase deficiency
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FBP2 |
fructose-bisphosphatase 2 |
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